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1.14.19.B8: [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase

This is an abbreviated version!
For detailed information about [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase, go to the full flat file.

Reaction

S-(3S)-beta-tyrosyl-[peptidyl-carrier-protein SgcC2]-L-cysteine
+
FADH2
+
Cl-
+
O2
+
H+
=
S-(S3)-3-chloro-beta-tyrosyl-[peptidyl-carrier-protein SgcC2]-L-cysteine
+
FAD
+ 2 H2O

Synonyms

SgcC3

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.B8 [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase

Reference

Reference on EC 1.14.19.B8 - [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lin, S.; van Lanen, S.G., Shen, B.
Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027
J. Am. Chem. Soc.
129
12432-12438
2007
Streptomyces globisporus
Manually annotated by BRENDA team