1.14.19.33: DELTA12 acyl-lipid conjugase (11E,13E-forming)

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For detailed information about DELTA12 acyl-lipid conjugase (11E,13E-forming), go to the full flat file.

Reaction

+ 2 ferrocytochrome b5 +

+ 2 H+ =

+ 2 ferricytochrome b5 + 2 H2O

Synonyms

DELTA12 desaturase, DELTA12 oleate desaturase, FADX, FADX-1A, FADX-1B, FADX-2, fatty acid DELTA12-conjugase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.19 With oxidation of a pair of donors resulting in the reduction of O₂ to two molecules of water

1.14.19.33 DELTA12 acyl-lipid conjugase (11E,13E-forming)

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Results	in table
8	AA Sequence
10	Cloned(Commentary)
1	Cofactor
3	General Information
3	Localization
10	Natural Substrates/ Products (Substrates)
9	Organism
1	Pathway
4	Protein Variants
4	Reaction
9	Reference
5	Source Tissue
24	Substrates and Products (Substrate)
15	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.14.19.33 - DELTA12 acyl-lipid conjugase (11E,13E-forming)

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DELTA12 acyl-lipid,ferrocytochrome-b5:oxygen 11,14 allylic oxidase (11E,13E-forming)

The enzyme, characterized from the plants Impatiens balsamina, Momordica charantia (bitter gourd) and Vernicia fordii (tung tree), converts a single cis double bond at carbon 12 to two conjugated trans bonds at positions 11 and 13. The enzyme from Vernicia fordii can also act as a 12(E) desaturase when acting on the monounsaturated fatty acids oleate and palmitoleate. cf. EC 1.14.19.16, linoleoyl-lipid Delta12 conjugase (11E,13Z-forming).