1.14.19.30: acyl-lipid (8-3)-desaturase
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For detailed information about acyl-lipid (8-3)-desaturase, go to the full flat file.
Word Map on EC 1.14.19.30
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1.14.19.30
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arachidonic
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polyunsaturated
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linoleic
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desaturation
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phospholipid
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desaturases
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pufas
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delta-6
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docosahexaenoic
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eicosapentaenoic
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dihomo-gamma-linolenic
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delta6-desaturase
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elongase
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monounsaturated
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alpha-linolenic
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gamma-linolenic
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stearoyl-coa
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mortierella
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omega-6
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alpina
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8-hydroxyoctanoic
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lc-pufas
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sesamin
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eicosatrienoic
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medicine
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agriculture
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diagnostics
- 1.14.19.30
-
arachidonic
-
polyunsaturated
-
linoleic
-
desaturation
- phospholipid
-
desaturases
-
pufas
-
delta-6
-
docosahexaenoic
-
eicosapentaenoic
-
dihomo-gamma-linolenic
- delta6-desaturase
- elongase
-
monounsaturated
-
alpha-linolenic
-
gamma-linolenic
- stearoyl-coa
-
mortierella
-
omega-6
- alpina
-
8-hydroxyoctanoic
-
lc-pufas
- sesamin
-
eicosatrienoic
- medicine
- agriculture
- diagnostics
Reaction
+ 2 ferrocytochrome b5 + + 2 H+ = + 2 ferricytochrome b5 + 2 H2O
Synonyms
acyl-lipid 5-desaturase, AL21, C20 DELTA5cis-desaturase, D5b, D5D, D5des, delta 5 desaturase, DELTA 5 fatty acid desaturase, delta-5 desaturase, DELTA-5-desaturase, DELTA5 desaturase, DELTA5 fatty acid desaturase, DELTA5-Des, DELTA5-desaturase, DELTA5-fatty acid desaturase, DELTA5-fatty-acid desaturase, DES5, desat7, FadA, FadB, FADS1, fads2b, FAT-4, fatty acid desaturase, PPDES5, PsD5Des
ECTree
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Cloned
Cloned on EC 1.14.19.30 - acyl-lipid (8-3)-desaturase
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expressed in CHO cells
expressed in Saccharomyces cerevisiae strain InvSc1
expressed in Saccharomyces cerevisiae strain SC334 and in transgenic canola seeds
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expressed in Saccharoymces cerevisiae strain CEN.PK 113-5D
expression in Saccharomyces cerevisiae
expression in the yeast Saccharomyces cerevisiae. The yeast cells acquire functional DELTA5-desaturase activity and are capable of synthesizing arachidonic acid from the substrate di-homo-gamma-linolenic acid
expression of the enzyme in Saccharomyces cerevisiae results in the production of the DELTA5-containing fatty acid arachidonic acid in cells that are provided di-homo-gamma-linolenic acid
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investigation of the effects of DELTA-5 and DELTA-6 desaturase on antibacterial and immunomodulatory activity in transgenic zebrafish infected with Vibrio alginolyticus. Overexpression of DELTA-5 and DELTA-6 desaturase enhances antibacterial activity at 4 and 12 h after injection of bacteria into muscle, as compared to controls. Expression of immune-related genes (IL-1b, IL-22, and TNF-a) is observed to be altered in transgenic fish after 4 h of bacterial infection, resulting in a significant decrease in the inflammatory response, as compared to control fish. Muscle-specific expression of transgenic desaturases in zebrafish not only enhances polyunsaturated fatty acid production, but also enhances antibacterial and anti-inflammatory activity