1.14.19.25: acyl-lipid omega-3 desaturase (cytochrome b5)
This is an abbreviated version!
For detailed information about acyl-lipid omega-3 desaturase (cytochrome b5), go to the full flat file.
Word Map on EC 1.14.19.25
-
1.14.19.25
-
linolenic
-
polyunsaturated
-
desaturases
-
pufas
-
alpha-linolenic
-
desaturation
-
flax
-
usitatissimum
-
linum
-
trienoic
-
omega-6
-
stearoyl-acp
-
medicine
- 1.14.19.25
-
linolenic
-
polyunsaturated
-
desaturases
-
pufas
-
alpha-linolenic
-
desaturation
- flax
- usitatissimum
-
linum
-
trienoic
-
omega-6
- stearoyl-acp
- medicine
Reaction
+ 2 ferrocytochrome b5 + + 2 H+ = + 2 ferricytochrome b5 + 2 H2O
Synonyms
BjFad3, DELTA15 desaturase, endoplasmic reticulum-type omega-3 fatty acid desaturase, ER-localized omega-3 FA desaturase, ER-type desaturase, ER-type omega-3 fatty acid desaturase, FAD3, FAD3-1, FAD3-2, FAD3A, FAD3B, FAD3C, fatty acid desaturase 3, LeFAD3, maw3, msdd17, omega-3 desaturase, omega-3 FA desaturase, omega-3 FAD, omega-3 fatty acid desaturase, omega3-desaturase, PfrFAD3, sdd17
ECTree
Advanced search results
Systematic Name
Systematic Name on EC 1.14.19.25 - acyl-lipid omega-3 desaturase (cytochrome b5)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
(9Z,12Z)-octadeca-9,12-dienoyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (15,16 cis-dehydrogenating)
This microsomal enzyme introduces a cis double bond three carbons away from the methyl end of a fatty acid incorporated into a glycerolipid. The distance from the carboxylic acid end of the molecule does not have an effect. The plant enzyme acts on carbon 15 of linoleoyl groups incorporated into both the sn-1 and sn-2 positions of the glycerol backbone of phosphatidylcholine and other phospholipids, converting them into alpha-linolenoyl groups. The enzyme from the fungus Mortierella alpina acts on gamma-linolenoyl and arachidonoyl groups, converting them into stearidonoyl and icosapentaenoyl groups, respectively [3]. cf. EC 1.14.19.35, sn-2 acyl-lipid omega-3 desaturase (ferredoxin).