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1.14.19.25: acyl-lipid omega-3 desaturase (cytochrome b5)

This is an abbreviated version!
For detailed information about acyl-lipid omega-3 desaturase (cytochrome b5), go to the full flat file.

Word Map on EC 1.14.19.25

Reaction

a linoleoyl-[glycerolipid]
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
an alpha-linolenoyl-[glycerolipid]
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

BjFad3, DELTA15 desaturase, endoplasmic reticulum-type omega-3 fatty acid desaturase, ER-localized omega-3 FA desaturase, ER-type desaturase, ER-type omega-3 fatty acid desaturase, FAD3, FAD3-1, FAD3-2, FAD3A, FAD3B, FAD3C, fatty acid desaturase 3, LeFAD3, maw3, msdd17, omega-3 desaturase, omega-3 FA desaturase, omega-3 FAD, omega-3 fatty acid desaturase, omega3-desaturase, PfrFAD3, sdd17

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.25 acyl-lipid omega-3 desaturase (cytochrome b5)

Substrates Products

Substrates Products on EC 1.14.19.25 - acyl-lipid omega-3 desaturase (cytochrome b5)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
a dihomo-gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
a (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
a gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
a stearidonoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
a linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
an alpha-linolenoyl-[glycerolipid] + ferricytochrome b5 + 2 H2O
show the reaction diagram
an arachidonoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
a (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
arachidonic acid + 2 ferrocytochrome b5 + O2 + 2 H+
eicosapentaenoic acid + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
-
-
?
arachidonoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
eicosapentaenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
-
?
linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
alpha-linolenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
omega-6 linoleic acid + 2 ferrocytochrome b5 + O2 + 2 H+
linolenic acid + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
best substrate
-
-
?
additional information
?
-