1.14.19.17: sphingolipid 4-desaturase

This is an abbreviated version, for detailed information about sphingolipid 4-desaturase, go to the full flat file.

Reaction

a dihydroceramide
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
a (4E)-sphing-4-enine ceramide
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

degenerative spermatocyte desaturase, Degs1, dehydroceramide desaturase, DELTA4 desaturase, DELTA4DES, DES-1, DES1, DHCD, dihydroceramide DELTA4-(E)-desaturase, dihydroceramide DELTA4-desaturase, dihydroceramide DELTA4-desaturase 1, dihydroceramide desaturase, LCB DELTA4 desaturase, MDES, membrane lipid desaturase, MLD, SPBC3B8.07c, sphingolipid DELTA4-desaturase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.17 sphingolipid 4-desaturase