1.14.18.5: sphingolipid C4-monooxygenase

This is an abbreviated version!
For detailed information about sphingolipid C4-monooxygenase, go to the full flat file.

Reaction

Synonyms

bifunctional sphingolipid D4-desaturase/C4-hydroxylase, DES2, DHS hydroxylase, dihydroceramide hydrolase, dihydroceramide hydroxylase, EC 1.14.13.169, LmjF_26_1670, SBH1, SBH2, SC4H, sphinganine C4-hydroxylase, sphinganine C4-monooxygenase, sphingolipid C4-hydroxylase, sphingolipid delta(4)-desaturase/C4-monooxygenase, sphingolipid hydroxylase, SUR2, Sur2p, SYR2, Syr2p

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.18.5 sphingolipid C4-monooxygenase

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Results	in table
30	AA Sequence
6	Cloned(Commentary)
2	Expression
9	General Information
3	KM Value [mM]
3	Localization
1	Metals/Ions
2	Molecular Weight [Da]
12	Organism
4	Pathway
19	Protein Variants
1	Reaction
12	Reference
5	Source Tissue
19	Substrates and Products (Substrate)
2	Subunits
37	Synonyms
1	Systematic Name

Expression

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Expression on EC 1.14.18.5 - sphingolipid C4-monooxygenase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

sphinganine hydroxylase activity in microsomes isolated from corn shoots treated with fumonisin B1 increases more than 3fold compared to controls

Zea mays

-

733207

the enzyme is up-regulated during keratinocyte differentiation

Homo sapiens

Q6QHC5

719485