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1.14.18.4: phosphatidylcholine 12-monooxygenase

This is an abbreviated version!
For detailed information about phosphatidylcholine 12-monooxygenase, go to the full flat file.

Word Map on EC 1.14.18.4

Reaction

a 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
a 1-acyl-2-[(12R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine
+ 2 ferricytochrome b5 +
H2O

Synonyms

castor DELTA12-hydroxylase, CFAH12, CFAH12 protein, CpFAH, CpFAH12, DELTA12 oleate hydroxylase, EC 1.14.13.26, FAH, FAH12, LFAH12, oleate 12-hydroxylase, oleate DELTA12-hydroxylase, oleate hydroxylase, oleoyl-12-hydroxylase, oxygenase, oleate DELTA12-mono, ricinoleic acid synthase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.4 phosphatidylcholine 12-monooxygenase

Reference

Reference on EC 1.14.18.4 - phosphatidylcholine 12-monooxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moreau, R.A.; Stumpf, P.K.
Recent studies of the enzymic synthesis of ricinoleic acid by developing castor beans
Plant Physiol.
67
672-676
1981
Ricinus communis
Manually annotated by BRENDA team
Van de Loo, F.J.; Broun, P.; Turner, S.; Somerville, C.
An oleate 12-hydroxylase from Ricinus communis L. is a fatty acyl desaturase homolog
Proc. Natl. Acad. Sci. USA
92
6743-6747
1995
Ricinus communis
Manually annotated by BRENDA team
Broun, P.; Boddupalli, S.; Somerville, C.
A bifunctional oleate 12-hydroxylase: desaturase from Lesquerella fendleri
Plant J.
13
201-210
1998
Physaria fendleri (O81094), Physaria fendleri
Manually annotated by BRENDA team
Lin, J.T.; McKeon, T.A.; Goodrich-Tanrikulu, M.; Stafford, A.E.
Characterization of oleoyl-12-hydroxylase in castor microsomes using the putative substrate, 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
Lipids
31
571-577
1996
Ricinus communis
Manually annotated by BRENDA team
Richards, D.E.; Taylor, R.D.; Murphy, D.J.
Localization and possible substrate requirement of the oleate 12-hydroxylase of developing Ricinus communis seeds
Plant Physiol. Biochem.
31
89-94
1993
Ricinus communis
-
Manually annotated by BRENDA team
Smith, M.A.; Moon, H.; Chowrira, G.; Kunst, L.
Heterologous expression of a fatty acid hydroxylase gene in developing seeds of Arabidopsis thaliana
Planta
217
507-516
2003
Physaria fendleri (O81094), Ricinus communis (Q41131), Ricinus communis
Manually annotated by BRENDA team
Meesapyodsuk, D.; Qiu, X.
An oleate hydroxylase from the fungus Claviceps purpurea: cloning, functional analysis, and expression in Arabidopsis
Plant Physiol.
147
1325-1333
2008
Claviceps purpurea
Manually annotated by BRENDA team
Dauk, M.; Lam, P.; Kunst, L.; Smith, M.A.
A FAD2 homologue from Lesquerella lindheimeri has predominantly fatty acid hydroxylase activity
Plant Sci.
173
43-49
2007
Physaria lindheimeri (A5HB93)
Manually annotated by BRENDA team
Dauk, M.; Lam, P.; Smith, M.
The role of diacylglycerol acyltransferase-1 and phospholipid: diacylglycerol acyltransferase-1 and -2 in the incorporation of hydroxy fatty acids into triacylglycerol in Arabidopsis thaliana expressing a castor bean oleate 12-hydroxylase gene
Botany
87
552-560
2009
Ricinus communis (D2CPE1)
-
Manually annotated by BRENDA team
Holic, R.; Yazawa, H.; Kumagai, H.; Uemura, H.
Engineered high content of ricinoleic acid in fission yeast Schizosaccharomyces pombe
Appl. Microbiol. Biotechnol.
95
179-187
2012
Claviceps purpurea
Manually annotated by BRENDA team
Yazawa, H.; Kumagai, H.; Uemura, H.
Secretory production of ricinoleic acid in fission yeast Schizosaccharomyces pombe
Appl. Microbiol. Biotechnol.
97
8663-8671
2013
Claviceps purpurea
Manually annotated by BRENDA team
Meesapyodsuk, D.; Chen, Y.; Ng, S.H.; Chen, J.; Qiu, X.
Metabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance
J. Lipid Res.
56
2102-2109
2015
Claviceps purpurea (B4YQU1), Claviceps purpurea
Manually annotated by BRENDA team
Lin, J.T.; Chen, J.M.; Chen, P.; Liao, L.P.; McKeon, T.A.
Molecular species of PC and PE formed during castor oil biosynthesis
Lipids
37
991-995
2002
Ricinus communis
Manually annotated by BRENDA team
Yazawa, H.; Ogiso, M.; Kumagai, H.; Uemura, H.
Suppression of ricinoleic acid toxicity by ptl2 overexpression in fission yeast Schizosaccharomyces pombe
Appl. Microbiol. Biotechnol.
98
9325-9337
2014
Claviceps purpurea (B4YQU1), Claviceps purpurea
Manually annotated by BRENDA team
Venegas-Caleron, M.; Sanchez, R.; Salas, J.J.; Garces, R.; Martinez-Force, E.
Molecular and biochemical characterization of the OLE-1 high-oleic castor seed (Ricinus communis L.) mutant
Planta
244
245-258
2016
Ricinus communis (Q41131), Ricinus communis, Ricinus communis OLE-1 (Q41131)
Manually annotated by BRENDA team