1.14.18.2: CMP-N-acetylneuraminate monooxygenase
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For detailed information about CMP-N-acetylneuraminate monooxygenase, go to the full flat file.
Word Map on EC 1.14.18.2
Reaction
Synonyms
CMAH, CMP Neu5Ac hydroxylase, CMP-N-acetylneuraminate hydroxylase, CMP-N-acetylneuraminate,NAD(P)H:oxygen oxidoreductase (hydroxylating), CMP-N-acetylneuraminic acid hydroxylase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase, cytidine monophosphate-N-acetylneuraminic acid hydroxylase, cytidine monophospho-N-acetylneuraminic acid hydroxylase, EC 1.14.13.45, oxygenase, cytidine monophosphoacetylneuraminate mono-, pcmah
ECTree
1.14.18.2 CMP-N-acetylneuraminate monooxygenaseAdvanced search results
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results (Source Tissue
Source Tissue on EC 1.14.18.2 - CMP-N-acetylneuraminate monooxygenase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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generation of a stable CHO cell line with significantly reduced levels of CMP-Neu5Ac hydroxylase activity and reduced amounts of N-glycolylneuraminic acid, using a rational antisense RNA strategy
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from thymus, spleen, lymph node and peripheral blood. Highest activity in peripheral blood lymphocytes
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traces of Neu5Gc found in serum by paper chromatography and in serum glycoproteins by HPLC analysis of per-O-benzoylated sialic acids
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no significant temporal alterations in the activity in foetal and newborn small intestine. Birth is followed by a 2-8fold decrease in activity, depending on the region of the small intestine. Increase in activity from duodenum to ileum
