1.14.18.2: CMP-N-acetylneuraminate monooxygenase

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For detailed information about CMP-N-acetylneuraminate monooxygenase, go to the full flat file.

Word Map on EC 1.14.18.2

1.14.18.2

n-glycolylneuraminic

neu5gc

sialic

xenotransplantation

cmp-neu5gc

n-glycolyl

hanganutziu-deicher

non-gal

human-like

xenoantigenicity

anti-neu5gc

hominid

alpha-1,3-galactosyltransferase

asterias

neu5gc-containing

medicine

synthesis

analysis

Reaction

+ 2 ferrocytochrome b5 +

+ 2 H+ =

+ 2 ferricytochrome b5 +

Synonyms

CMAH, CMP Neu5Ac hydroxylase, CMP-N-acetylneuraminate hydroxylase, CMP-N-acetylneuraminate,NAD(P)H:oxygen oxidoreductase (hydroxylating), CMP-N-acetylneuraminic acid hydroxylase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase, cytidine monophosphate-N-acetylneuraminic acid hydroxylase, cytidine monophospho-N-acetylneuraminic acid hydroxylase, EC 1.14.13.45, oxygenase, cytidine monophosphoacetylneuraminate mono-, pcmah

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor

1.14.18.2 CMP-N-acetylneuraminate monooxygenase

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Results	in table
11	Activating Compound
710	AA Sequence
3	Application
1	CAS Registry Number
14	Cloned(Commentary)
30	Cofactor
37	Disease/ Diagnostics
12	General Information
4	General Stability
52	Inhibitors
12	KM Value [mM]
18	Localization
10	Metals/Ions
9	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
53	Organism
2	Pathway
6	pH Optimum
1	pH Range
1	Posttranslational Modification
16	Protein Variants
8	Purification (Commentary)
1	Reaction
5	Reaction Type
53	Reference
62	Source Tissue
4	Specific Activity [micromol/min/mg]
4	Storage Stability
47	Substrates and Products (Substrate)
5	Subunits
31	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Molecular Weight

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Molecular Weight on EC 1.14.18.2 - CMP-N-acetylneuraminate monooxygenase

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17000

gel filtration

56000

gel filtration

58000

gel filtration

60000

gel filtration

64000

1 * 64000, SDS-PAGE

65000

1 * 65000, SDS-PAGE

75000

C1K3L2

determined by SDS-PAGE and Western Blot analysis

701238