Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.18.1: tyrosinase

This is an abbreviated version!
For detailed information about tyrosinase, go to the full flat file.

Word Map on EC 1.14.18.1

Reaction

2 L-dopa +

O2
= 2 dopaquinone + 2 H2O

Synonyms

AbPPO1, AbPPO4, AbTYR, aurone synthase, catalase-phenol oxidase, catechol oxidase, catecholase, CATPO, chlorogenic acid oxidase, chlorogenic oxidase, cresolase, cresolase/monophenolase, CsPPO, CZA14Tyr, deoxy-tyrosinase, dihydroxy-L-phenylalanine:oxygen oxidoreductase, Diphenol oxidase, diphenolase, dopa oxidase, EC 1.10.3.1, EC 1.14.17.2, Hc-derived phenoloxidase, Hc-phenoloxidase, HcPO, HdPO, hemocyanin-derived phenoloxidase, jrPPO1, jrTYR, L-DOPA monophenolase, L-DOPA oxidase, L-DOPA:oxygen oxidoreductase, L-tyrosine hydroxylase, MdPPO1, melC2, MelC2 tyrosinase, met-tyrosinase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, monophenol monooxidase, monophenol monooxygenase, monophenol monoxygenase, monophenol oxidase, monophenol oxygen oxidoreductase, monophenol, 3,4-dihydroxy L-phenylalanine (L-DOPA):oxygen oxidoreductase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, monophenol, dihydroxy-L-phenylalanine:oxygen oxidoreductase, monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, monophenol, L-Dopa: oxidoreductase, monophenol, L-DOPA: oxygen oxidoreductase, monophenol, o-diphenol: oxygen oxidoreductase, monophenol, o-diphenol:O2 oxidoreductase, monophenol, o-diphenol:oxygen oxido-reductase, monophenol, o-diphenol:oxygen oxidoreductase, monophenol, polyphenol oxidase, monophenol: dioxygen oxidoreductases, hydroxylating, monophenolase, monphenol mono-oxygenase, More, mTyr, murine tyrosinase, mushroom tyrosinase, mushroom tyrosine, N-acetyl-6-hydroxytryptophan oxidase, o-diphenol oxidase, o-diphenol oxidoreductase, o-diphenol oxygen oxidoreductase, o-diphenol: O2 oxidoreductase, o-diphenol: oxidoreductase, o-diphenol:O2 oxidoreductase, o-diphenol:oxygen oxidoreductase, o-diphenolase, OCA1, Orf13, oxygen oxidoreductase, phenol oxidase, phenol oxidases, phenolase, phenoloxidase, PO, polyaromatic oxidase, polyphenol oxidase, polyphenol oxidase 3, polyphenol oxidase 4, polyphenol oxidase B, polyphenolase, polyphenoloxidase, PotPPO, PPO, PPO 3, PPO B, PPO1, PPO2, PPO3, pro-PO III, prophenoloxidase III, pyrocatechol oxidase, SPRTyr, ST94, ST94t, tryosinase, tryrosinase, TY, tyr, TYR1, TYR2, tyrA, TyrBm, tyrosinase, tyrosinase 2, tyrosinase 4, tyrosinase diphenolase, tyrosine-dopa oxidase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.1 tyrosinase

Turnover Number

Turnover Number on EC 1.14.18.1 - tyrosinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
9.94
2-Methylresorcinol
-
pH 7.0, 25°C
554 - 632
3,4-dihydroxyphenyl propionic acid
5.9 - 433.1
3,4-dihydroxyphenylacetic acid
607.2
3,4-Dihydroxyphenylpropionic acid
-
-
544
3-(3,4-dihydroxyphenyl) propionic acid
-
3
3-(3,5-dihydroxyphenyl)-1-propanoic acid
recombinant enzyme, pH 7.2, 37°C
0.9
3-chlorophenol
-
in 100 mM phosphate buffer, pH 6.8, at 25°C
3
3-Fluorophenol
-
-
12.1
3-Hydroxybenzyl alcohol
-
-
46.8
3-methoxyphenol
-
-
6
3-[2-(3,4-dihydroxyphenyl)ethylaminocarbonyl]-3-methyl-1-(4-ethoxycarbonylphenyl)triazene
-
in phosphate buffer (pH 7.4), at 37°C
0.6
3-[2-(4-hydroxyphenyl)ethylaminocarbonyl]-3-methyl-1-(4-cyanophenyl)triazene
-
in phosphate buffer (pH 7.4), at 37°C
6.9
4-Bromophenol
-
pH and temperature not specified in the publication
859.2
4-Chlorocatechol
-
-
4.6 - 5.6
4-Chlorophenol
132 - 202.2
4-ethoxyphenol
802.3
4-Ethylcatechol
-
-
6
4-ethylresorcinol
-
pH 7.0, 25°C
10.5 - 10.54
4-Fluorophenol
184 - 274.9
4-hydroxyanisole
0.19
4-hydroxybenzaldehyde
-
pH and temperature not specified in the publication
20 - 88.2
4-Hydroxybenzyl alcohol
66.7 - 134
4-hydroxyphenyl propionic acid
44.3 - 250
4-hydroxyphenyl acetic acid
66.7
4-hydroxyphenyl propionic acid
-
-
43 - 66.7
4-hydroxyphenylpropionic acid
2.73
4-iodophenol
-
pH and temperature not specified in the publication
184 - 184.2
4-methoxyphenol
12 - 7220
4-methylcatechol
14.76
4-Methylphenol
-
pH and temperature not specified in the publication
7.73
4-methylresorcinol
-
pH 7.0, 25°C
0.9
4-nitrocatechol
-
-
294
4-t-butylcatechol
-
13.2
4-t-butylphenol
-
20.5 - 1650
4-tert-butylcatechol
5.61
4-tert-butylphenol
-
pH and temperature not specified in the publication
4.43
alpha-arbutin
-
pH 7.0, 25°C
3.7 - 3.77
beta-arbutin
1450
caffeic acid
-
-
44 - 2960
catechol
1650
chlorogenic acid
-
-
0.92
D-ascorbic acid
-
-
6 - 117
D-Dopa
8 - 160
D-Tyr
0.3 - 2.27
D-tyrosine
1.95
deoxyarbutin
pH and temperature not specified in the publication
4.48
diphenol
Helix vulgaris
-
-
0.6
DL-2-methyltyrosine
-
-
1170
DL-dopa
-
-
74.2
DL-tyrosine
-
-
26.7 - 4940
Dopa
35.5
dopa methyl ester
-
-
29.9 - 2540
dopamine
123 - 928
esculetin
28.2
gallic acid
-
-
3 - 7.2
Gly-Gly-L-Tyr
3.1 - 4.2
Gly-L-Tyr-Gly
1.5
H2O2
-
at pH 8.0 and 37°C
4630
Hydrocaffeic acid
-
-
101.5
hydroquinone
-
pH 7.0, 25°C
229
Hydroxyhydroquinone
-
pH and temperature not specified in the publication
0.6
L-alpha-methyl tyrosine
-
-
44.3
L-alpha-methyldopa
-
-
0.97
L-ascorbic acid
-
-
0.04 - 1810
L-Dopa
57 - 187
L-dopa methyl ester
2.28 - 29.4
L-isoproterenol
7.9 - 320
L-Tyr
3.2 - 4
L-Tyr-Gly-Gly
2.5 - 19.5
L-tyrosinase
-
0.576 - 100
L-tyrosine
3.4 - 235
L-tyrosine methyl ester
2.24 - 8.9
methyl 3-hydroxy-L-tyrosinate
80.2
methyl gallate
-
-
2.66 - 3.5
o-Diphenol
5.39
oxyresveratrol
-
pH 7.0, 25°C
107
p-Cresol
-
3.2 - 14.36
phenol
8.1 - 860
protocatechuic acid
1.5 - 336
Protocatechuic aldehyde
9.7 - 1280
pyrogallol
18.34
resorcinol
-
pH 7.0, 25°C
1.9 - 160
tyramine
0.0117 - 0.0217
tyrosine