1.14.17.1: dopamine beta-monooxygenase
This is an abbreviated version!
For detailed information about dopamine beta-monooxygenase, go to the full flat file.
Word Map on EC 1.14.17.1
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1.14.17.1
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catecholamine
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noradrenergic
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norepinephrine
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nerve
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sympathetic
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noradrenaline
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adrenal
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innervation
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medulla
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fiber
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dopaminergic
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neuropeptide
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chromaffin
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adrenergic
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monoamine
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neurotransmitter
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ganglia
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coeruleus
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hypothalamus
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catecholaminergic
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phenylethanolamine
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npy
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epinephrine
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cholinergic
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adrenaline
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phenylethanolamine-n-methyltransferase
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n-methyltransferase
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varicosity
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vasoactive
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rostrally
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reserpine
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gene-related
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catecholamine-synthesizing
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disulfiram
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peptidylglycine
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preganglionic
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adrenomedullary
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th-immunoreactive
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orthostatic
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preoptic
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ventrolateral
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monoaminergic
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parabrachial
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saporin
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intermediolateral
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hydroxylase-immunoreactive
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cytoarchitectonic
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medicine
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drug development
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postrema
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diagnostics
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histofluorescence
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alpha-methyl-p-tyrosine
- 1.14.17.1
- catecholamine
-
noradrenergic
- norepinephrine
- nerve
-
sympathetic
- noradrenaline
- adrenal
-
innervation
- medulla
- fiber
-
dopaminergic
-
neuropeptide
-
chromaffin
-
adrenergic
-
monoamine
-
neurotransmitter
- ganglia
- coeruleus
- hypothalamus
-
catecholaminergic
- phenylethanolamine
- npy
- epinephrine
-
cholinergic
- adrenaline
-
phenylethanolamine-n-methyltransferase
- n-methyltransferase
-
varicosity
-
vasoactive
-
rostrally
- reserpine
-
gene-related
-
catecholamine-synthesizing
- disulfiram
- peptidylglycine
-
preganglionic
-
adrenomedullary
-
th-immunoreactive
-
orthostatic
-
preoptic
-
ventrolateral
-
monoaminergic
-
parabrachial
- saporin
-
intermediolateral
-
hydroxylase-immunoreactive
-
cytoarchitectonic
- medicine
- drug development
- postrema
- diagnostics
-
histofluorescence
- alpha-methyl-p-tyrosine
Reaction
Synonyms
3,4-dihydroxy-phenylethylamine, ascorbate: oxygen oxidoreductase (3-hydroxylating), 3,4-dihydroxyphenethylamine beta-oxidase, 3,4-dihydroxyphenylethylamine beta-hydoxylase, 4-(2-aminoethyl)pyrocatechol beta-oxidase, DbetaH, DbetaM, DBH, DBM, Dopa beta-hydroxylase, dopamine beta hydroxylase, dopamine beta-hydrolase, dopamine beta-hydroxylase, dopamine beta-mono-oxygenase, dopamine beta-monooxygenase, dopamine beta-oxidase, dopamine hydroxylase, dopamine(3,4-dihydroxyphenethylamine)beta-mono-oxygenase, dopamine-B-hydroxylase, dopamine-beta hydroxylase, dopamine-beta-hydroxylase, dopamine-beta-monooxygenase, EC 1.14.2.1, gDBH, LvDBH, MDBH, oxygenase, dopamine beta-mono-, pDbetaH, phenylamine beta-hydroxylase, plasma DbetaH activity, plasma dopamine beta-hydroxylase, plDbetaH, SDBH, TBetaM, tyramine beta-monooxygenase
ECTree
1.14.17.1 dopamine beta-monooxygenaseAdvanced search results
results (
results (KM Value
KM Value on EC 1.14.17.1 - dopamine beta-monooxygenase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
3.8
2-aminoindane
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37°C, 0.2 M acetate buffe, pI 6, with 30 mM NEM, 1 mM K4Fe(CN)6, 5 mM CuSO4
0.0906
beta,beta-dideuterated tyramine
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at 10 mM ascorbate, 0.907 mM O2, pH 6 and 35°C
0.145
beta,beta-dideuterated tyramine
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at 10 mM ascorbate, 0.395 mM O2, pH 6 and 35°C
0.177
beta,beta-dideuterated tyramine
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at 10 mM ascorbate, 0.119 mM O2, pH 6 and 35°C
0.178
beta,beta-dideuterated tyramine
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at 10 mM ascorbate, 0.215 mM O2, pH 6 and 35°C
0.193
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 1.039 mM O2, pH 6 and 35°C
0.203
beta,beta-dideuterated tyramine
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at 10 mM ascorbate, 0.587 mM O2, pH 6 and 35°C
0.231
beta,beta-dideuterated tyramine
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at 10 mM ascorbate, 0.056 mM O2, pH 6 and 35°C
0.233
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 0.907 mM O2, pH 6 and 35°C
0.245
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 0.214 mM O2, pH 6 and 35°C
0.257
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 0.110 mM O2, pH 6 and 35°C
0.316
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 0.598 mM O2, pH 6 and 35°C
0.328
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 0.416 mM O2, pH 6 and 35°C
0.341
beta,beta-dideuterated tyramine
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at 50 mM ascorbate, 0.063 mM O2, pH 6 and 35°C
0.5 - 2
tyramine
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enzyme from serum of 5-weeks-old rats, at 37°C, pH not specified in the publication
0.79
tyramine
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enzyme from serum of 2-weeks-old rats, at 37°C, pH not specified in the publication
0.92
tyramine
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enzyme from serum of 8-weeks-old rats, at 37°C, pH not specified in the publication
1.22
tyramine
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enzyme from serum of 1-weeks-old rats, at 37°C, pH not specified in the publication
1.37
tyramine
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enzyme from serum of 12-weeks-old rats, at 37°C, pH not specified in the publication
1.6
tyramine
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enzyme from serum of 15-weeks-old rats, at 37°C, pH not specified in the publication
2.1
tyramine
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enzyme from serum of 27-weeks-old rats, at 37°C, pH not specified in the publication
additional information
additional information
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Km of ascorbate, tyramine and O2 as a function of pH and fumarate activation
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additional information
additional information
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Km of benzyl cyanide analogs with or without 6% dimethylformamide
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additional information
additional information
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comparison of Km of native enzyme and dimeric and tetrameric species after treatment with dithiothreitol and iodoacetamide
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additional information
additional information
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Km of N,N-dimethyl-1,4-phenylenediamine and ascorbic acid derivatives
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