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1.14.16.6: mandelate 4-monooxygenase

This is an abbreviated version!
For detailed information about mandelate 4-monooxygenase, go to the full flat file.

Reaction

(S)-2-Hydroxy-2-phenylacetate
+
a 5,6,7,8-tetrahydropteridine
+
O2
=
(S)-4-hydroxymandelate
+
a 4a-hydroxy-5,6,7,8-tetrahydropteridine

Synonyms

L-mandelate-4-hydroxylase, mandelic acid 4-hydroxylase, oxygenase, mandelate 4-mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.16.6 mandelate 4-monooxygenase

Substrates Products

Substrates Products on EC 1.14.16.6 - mandelate 4-monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-2-hydroxy-2-phenylacetate + tetrahydropteridine
(S)-4-hydroxymandelate + dihydropteridine + H2O
show the reaction diagram
(S)-2-hydroxy-2-phenylacetate + tetrahydropteridine + O2
?
show the reaction diagram
-
i.e. L-mandelate, first step of oxidative degradation of L-mandelate by Pseudomonas convexa
-
-
?