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1.14.16.5: alkylglycerol monooxygenase

This is an abbreviated version!
For detailed information about alkylglycerol monooxygenase, go to the full flat file.

Word Map on EC 1.14.16.5

Reaction

1-O-alkyl-sn-glycerol
+
a 5,6,7,8-tetrahydropteridine
+
O2
=
1-O-(1-hydroxyalkyl)-sn-glycerol
+
a 4a-hydroxy-5,6,7,8-tetrahydropteridine

Synonyms

AGMO, alkylglycerol mono-oxygenase, alkylglycerol monooxygenase, EC 1.14.99.17, glyceryl ether hydroxylase, glyceryl ether monooxygenase, glyceryl ether oxidase, glyceryl ether oxygenase, glyceryl ether-cleaving enzyme, glyceryl etherase, glyceryl-ether cleaving enzyme, O-alkylglycerol monooxygenase, oxygenase, glyceryl ether mono-, PRUB680

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.16.5 alkylglycerol monooxygenase

Inhibitors

Inhibitors on EC 1.14.16.5 - alkylglycerol monooxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(NH4)2Mo7O24
-
-
1,10-phenanthroline
2-(1-octadecylthio)ethanol
-
reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin
3-(1-octadecylthio)propan-1,2-diol
-
0.5 mM, 64% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin
8-hydroxyquinoline
8-Hydroxyquinoline-5-sulfonic acid
-
1.0 mM, 13% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin
CHAPS
-
0.2% or 0.5%, activity is reduced by ca. 15% after 30 min
Digitonin
-
-
H2O2
-
catalase protects from inactivation
hexadecan-1,2-diol
-
reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin
hexadecyl phosphocholine
-
-
hexadecyl-L-alpha-lyso-phosphatidylcholine
-
competitive
hexadecylphosphocholine
-
-
Mega-10
myristoyl L-alpha-lyso-phosphatidylcholine
-
-
N5-methyltetrahydrobiopterin
-
-
octadecan-1-ol
octadecanol
-
competitive
palmitoyl L-alpha-lyso-phosphatidylcholine
-
-
Phenanthroline
-
competitive inhibitor
tetradecanoyl-L-alpha-lyso-phosphatidylcholine
-
competitive
tetradecyl phosphocholine
-
-
tetradecylphosphocholine
-
competitive
Triton X-100
-
6% loss of activity at 0.1% detergent and 59% loss of activity at 0.3% detergent