1.14.16.4: tryptophan 5-monooxygenase

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For detailed information about tryptophan 5-monooxygenase, go to the full flat file.

Word Map on EC 1.14.16.4

1.14.16.4

serotonin

serotonergic

raphe

5-hydroxytryptamine

monoamine

dorsal

dopamine

neurotransmitter

hippocampus

antidepressant

reuptake

5-hydroxytryptophan

anxiety

psychiatric

midbrain

striatum

hypothalamus

neurochemical

5-hydroxyindoleacetic

mood

enterochromaffin

neurotransmission

5-hiaa

p-chlorophenylalanine

fluoxetine

pineal

brainstem

alpha-methyl-p-tyrosine

monoaminergic

5,7-dihydroxytryptamine

analysis

methamphetamine

autoreceptors

slc6a4

immobility

pargyline

n-acetylserotonin

neostriatal

5-httlpr

medicine

citalopram

antidepressant-like

carcinoid

biopterins

impulsivity

oxidase-a

tetrahydropterins

fenfluramine

impulsive

8-oh-dpat

5-hydroxyindole

drug development

3,4-methylenedioxymethamphetamine

Reaction

a 4a-hydroxy-5,6,7,8-tetrahydropteridine

Synonyms

hTPH2, indoleacetic acid-5-hydroxylase, L-tryptophan 5-hydroxylase, L-tryptophan hydroxylase, oxygenase, tryptophan 5-mono-, peripheral tryptophan hydroxylase, PTMO, putative tryptophan monooxygenase, TH2, TPH, TPH-1, TPH-2, TPH1, TPH2, TRpOH, tryptophan 5-hydroxylase, tryptophan 5-monooxygenase, tryptophan hydroxylase, tryptophan hydroxylase 1, tryptophan hydroxylase 2, tryptophan hydroxylase I, tryptophan hydroxylase isoform 1, tryptophan hydroxylase isoform 2, tryptophan hydroxylase isoform2, tryptophan hydroxylase type I, tryptophan hydroxylase-1, tryptophan hydroxylase-2, tryptophan-5-hydroxylase

Results	in table
34	Activating Compound
1884	AA Sequence
7	Application
1	CAS Registry Number
66	Cloned(Commentary)
9	Cofactor
7	Crystallization (Commentary)
662	Disease/ Diagnostics
8	Expression
8	General Information
23	General Stability
173	IC50 Value
243	Inhibitors
23	Ki Value [mM]
127	KM Value [mM]
13	Localization
25	Metals/Ions
46	Molecular Weight [Da]
110	Natural Substrates/ Products (Substrates)
298	Organism
6	Pathway
28	PDB ID
17	pH Optimum
3	pH Range
1	pH Stability
6	Posttranslational Modification
80	Protein Variants
45	Purification (Commentary)
3	Reaction
3	Reaction Type
154	Reference
230	Source Tissue
34	Specific Activity [micromol/min/mg]
15	Storage Stability
242	Substrates and Products (Substrate)
25	Subunits
259	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
7	Temperature Stability [°C]
17	Turnover Number [1/s]

1.14.16.4: tryptophan 5-monooxygenase

Reaction

Synonyms

ECTree

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Organism

Organism on EC 1.14.16.4 - tryptophan 5-monooxygenase