1.14.15.19: C-19 steroid 1alpha-hydroxylase
This is an abbreviated version!
For detailed information about C-19 steroid 1alpha-hydroxylase, go to the full flat file.
Word Map on EC 1.14.15.19
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1.14.15.19
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sorangium
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cellulosum
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myxobacterium
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regioselective
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biocatalyst
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adrenodoxin
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asparagine
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11-deoxycorticosterone
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androstenedione
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pharmacology
- 1.14.15.19
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sorangium
- cellulosum
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myxobacterium
-
regioselective
-
biocatalyst
- adrenodoxin
- asparagine
- 11-deoxycorticosterone
- androstenedione
- pharmacology
Reaction
Synonyms
C-19 steroid 1alpha-hydroxylase, CYP260A1
ECTree
1.14.15.19 C-19 steroid 1alpha-hydroxylaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.14.15.19 - C-19 steroid 1alpha-hydroxylase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
11-oxoandrostenedione + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
1alpha-hydroxy-11-oxoandrostenedione + H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
Escherichia coli-based whole-cell biocatalyst system
-
-
?
androstenedione + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
1alpha-hydroxyandrostenedione + H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
Escherichia coli-based whole-cell biocatalyst system
-
-
?
testosterone + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
1alpha-hydroxytestosterone + H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
testosterone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
1alpha-hydroxytestosterone + H2O + oxidized ferredoxin [iron-sulfur] cluster
(+)-nootkatone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
?
-
-
-
?
(+)-nootkatone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
?
-
-
-
?
androstenedione + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
?
-
-
-
?
androstenedione + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
?
-
-
-
?
testosterone + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
1alpha-hydroxytestosterone + H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
-
-
-
-
?
testosterone + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
1alpha-hydroxytestosterone + H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
Escherichia coli-based whole-cell biocatalyst system
Escherichia coli-based whole-cell biocatalyst system produces a mixture (1:2.5:3) of an unknown compound and 1alpha- and 9alpha-hydroxytestosterone acetate
-
?
testosterone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
1alpha-hydroxytestosterone + H2O + oxidized ferredoxin [iron-sulfur] cluster
-
-
-
?
testosterone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
1alpha-hydroxytestosterone + H2O + oxidized ferredoxin [iron-sulfur] cluster
-
-
-
?
zerumbone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
?
-
-
-
?
zerumbone + reduced ferredoxin [iron-sulfur] cluster + O2 + H+
?
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-
-
?
