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1.14.14.25: cholesterol 24-hydroxylase

This is an abbreviated version!
For detailed information about cholesterol 24-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.25

Reaction

cholesterol
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
(24S)-cholest-5-ene-3beta,24-diol
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

24S-hydroxylase, CH24H, cholesterol 24-hydroxylase, cholesterol 24-monooxygenase, cholesterol 24S hydroxylase, cholesterol 24S-hydroxylase, cholesterol hydroxylase, cholesterol-24S-hydroxylase, CYP46, CYP46A, CYP46A1, cytochrome P-450 46A1, cytochrome P450 46A1, cytochrome P450 cholesterol 24-hydroxylase, EC 1.14.13.98

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.25 cholesterol 24-hydroxylase

Sequence

topprint

Sequence on EC 1.14.14.25 - cholesterol 24-hydroxylase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CP46A_HUMAN
500
0
56821
Swiss-Prot
Secretory Pathway (Reliability: 2)
CP46A_MOUSE
500
0
56814
Swiss-Prot
Secretory Pathway (Reliability: 2)
A0A8B6F7M3_MYTGA
507
1
58512
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8B6FAV5_MYTGA
390
0
44956
TrEMBL
other Location (Reliability: 4)
A0A6J8F1J5_MYTCO
502
1
58024
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8B6GZJ7_MYTGA
501
1
57149
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8B6F693_MYTGA
502
1
57877
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8B6F959_MYTGA
412
0
47476
TrEMBL
other Location (Reliability: 1)
A0A6J8E359_MYTCO
435
0
49974
TrEMBL
other Location (Reliability: 2)
A0A6J8DZ45_MYTCO
473
0
54332
TrEMBL
other Location (Reliability: 2)
A5WWJ0_DANRE
501
0
57798
TrEMBL
Chloroplast (Reliability: 2)
F7EN52_RAT
525
0
59379
TrEMBL
-
Q7SYY2_XENLA
503
0
57790
TrEMBL
-
CP46A_HUMAN
500
0
56821
Swiss-Prot
-