1.14.14.25: cholesterol 24-hydroxylase

This is an abbreviated version, for detailed information about cholesterol 24-hydroxylase, go to the full flat file.

Reaction

cholesterol
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(24S)-cholest-5-ene-3beta,24-diol
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

24S-hydroxylase, CH24H, cholesterol 24-hydroxylase, cholesterol 24-monooxygenase, cholesterol 24S hydroxylase, cholesterol 24S-hydroxylase, cholesterol hydroxylase, cholesterol-24S-hydroxylase, CYP46, CYP46A, CYP46A1, cytochrome P-450 46A1, cytochrome P450 46A1, cytochrome P450 cholesterol 24-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.25 cholesterol 24-hydroxylase