1.14.14.17: squalene monooxygenase

This is an abbreviated version, for detailed information about squalene monooxygenase, go to the full flat file.

Reaction

squalene
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(3S)-2,3-epoxy-2,3-dihydrosqualene
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP17, cytochrome P450 17alpha hydroxylase/17,20 lyase, Erg1, Erg1 protein, Erg1p, hydroxylase, squalene, oxygenase, squalene mono-, SE, SQE3, SQLE, squalen expoxidase, squalene 2,3-oxidocyclase, squalene epoxidase, squalene epoxidase 1, squalene epoxidase 3, squalene hydroxylase, squalene mono-oxygenase, squalene oxydocyclase, squalene-2,3-epoxidase, squalene-2,3-epoxide cyclase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.17 squalene monooxygenase