1.14.13.B3: nicotine demethylase

This is an abbreviated version, for detailed information about nicotine demethylase, go to the full flat file.

Reaction

Nicotine
+
NADPH
+
O2
+
H+
=
Nornicotine
+
formaldehyde
+
NADP+
+
H2O

Synonyms

CYP2A6, CYP2B6, CYP82E, CYP82E1, CYP82E10, CYP82E2, CYP82E3, CYP82E4, CYP82E5v2, nicotine N-demethylase, NND

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.B3 nicotine demethylase