1.14.13.69: alkene monooxygenase

This is an abbreviated version!
For detailed information about alkene monooxygenase, go to the full flat file.

Reaction

Synonyms

AkMO, alkene epoxygenase, alkene monooxygenase, AMO, ethene MO, EtnABCD, EtnC, etnD, IsoMO, isoprene monooxygenase, More, PmoABCD, propene MO, propene monooxygenase, XAMO

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.69 alkene monooxygenase

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Results	in table
3	Activating Compound
7	AA Sequence
2	Application
1	CAS Registry Number
7	Cloned(Commentary)
16	Cofactor
2	Expression
4	General Information
12	Inhibitors
3	KM Value [mM]
10	Metals/Ions
9	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
125	Organism
7	Pathway
3	pH Optimum
2	Protein Variants
5	Purification (Commentary)
1	Reaction
4	Reaction Type
43	Reference
1	Renatured (Commentary)
7	Source Tissue
5	Specific Activity [micromol/min/mg]
86	Substrates and Products (Substrate)
23	Subunits
27	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.14.13.69 - alkene monooxygenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

ethene + NADH + H+ + O2

?

2 entries

ethene + NADH + H+ + O2

oxirane + NAD+ + H2O

2 entries

isoprene + NADH + H+ + O2

isoprene epoxide + NAD+ + H2O

Rhodococcus sp. AD45

-

-

763983

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

10 entries

propene + NADH + O2

1,2-epoxypropane + NAD+ + H2O

3 entries

vinyl chloride + NADH + H+ + O2

?

2 entries

additional information

?

-

5 entries

ethene + NADH + H+ + O2

?

Nocardioides sp.

-

-

677851

-

-

?

ethene + NADH + H+ + O2

?

Nocardioides sp. JS614 / ATCC BAA-499

-

-

677851

-

-

?

ethene + NADH + H+ + O2

oxirane + NAD+ + H2O

Mycolicibacterium chubuense

-

-

763955

-

-

?

ethene + NADH + H+ + O2

oxirane + NAD+ + H2O

Mycolicibacterium chubuense NBB4

-

-

763955

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Gordonia rubripertincta

-

constitutive enzyme

285337

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Gordonia rubripertincta B-276

-

constitutive enzyme

285337

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Mycolicibacterium chubuense

-

-

763955

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Mycolicibacterium chubuense NBB4

-

-

763955

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Rhodococcus rhodochrous

-

-

728009

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Rhodococcus rhodochrous B-276

-

-

728009

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Xanthobacter sp.

-

induction by propylene and propylene oxide and a variety of aliphatic and chlorinated alkenes and epoxides

285336

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Xanthobacter sp.

-

the inducible enzyme is central to the bacterial metabolism of aliphatic alkenes. Enzyme is expressed during growth of Xanthobacter on aliphatic alkenes or epoxides and repressed during growth on other carbon sources

285342

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Xanthobacter sp. Py2

-

induction by propylene and propylene oxide and a variety of aliphatic and chlorinated alkenes and epoxides

285336

-

-

?

propene + NADH + H+ + O2

1,2-epoxypropane + NAD+ + H2O

Xanthobacter sp. Py2

-

the inducible enzyme is central to the bacterial metabolism of aliphatic alkenes. Enzyme is expressed during growth of Xanthobacter on aliphatic alkenes or epoxides and repressed during growth on other carbon sources

285342

-

-

?

propene + NADH + O2

1,2-epoxypropane + NAD+ + H2O

Rhodococcus rhodochrous

-

enables the growth on propene as sole carbon and energy source

658683

-

-

?

propene + NADH + O2

1,2-epoxypropane + NAD+ + H2O

Rhodococcus rhodochrous B-276

-

enables the growth on propene as sole carbon and energy source

658683

-

-

?

propene + NADH + O2

1,2-epoxypropane + NAD+ + H2O

Xanthobacter autotrophicus

-

-

658775

-

-

?

vinyl chloride + NADH + H+ + O2

?

Nocardioides sp.

-

-

677851

-

-

?

vinyl chloride + NADH + H+ + O2

?

Nocardioides sp. JS614 / ATCC BAA-499

-

-

677851

-

-

?

additional information

?

-

Nocardioides sp.

-

alkene monooxygenase and epoxyalkane:coenzyme M transferase are the initial enzymes of vinyl chloride and ethene biodegradation in strain JS614

677851

-

-

?

additional information

?

-

Nocardioides sp.

-

ethene and propene are transformed by ethene-grown and propene-grown/EtO-induced JS614 to ethene oxide and propene oxide, respectively

710973

-

-

?

additional information

?

-

Nocardioides sp. JS614 / ATCC BAA-499

-

alkene monooxygenase and epoxyalkane:coenzyme M transferase are the initial enzymes of vinyl chloride and ethene biodegradation in strain JS614

677851

-

-

?

additional information

?

-

Nocardioides sp. JS614 / ATCC BAA-499

-

ethene and propene are transformed by ethene-grown and propene-grown/EtO-induced JS614 to ethene oxide and propene oxide, respectively

710973

-

-

?

additional information

?

-

Trametes hirsuta

-

alternative alkene cleavage mechanism by incorporating 2 oxygen atoms of different oxygen molecules

698495

-

-

?