1.14.13.67: quinine 3-monooxygenase

This is an abbreviated version, for detailed information about quinine 3-monooxygenase, go to the full flat file.

Reaction

Quinine
+
NADPH
+
H+
+
O2
=
3-hydroxyquinine
+
NADP+
+
H2O

Synonyms

CYP2C19, CYP3A, CYP3A4, CYPIIIA4, cytochrome P450 isoform, NF-25, Nifedipine oxidase, P450-PCN1, quinine 3-hydroxylase, Quinine 3-monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.67 quinine 3-monooxygenase