1.14.13.63: 3-hydroxyphenylacetate 6-hydroxylase

This is an abbreviated version!
For detailed information about 3-hydroxyphenylacetate 6-hydroxylase, go to the full flat file.

Reaction

Synonyms

3,4-dihydroxyphenylacetate 6-hydroxylase, 3-Hydroxyphenylacetate 6-monooxygenase, CYP504B, m-Hydroxyphenylacetate 6-hydroxylase, More, Oxygenase, 3-hydroxyphenylacetate 6-mono

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase

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Results	in table
1	Activating Compound
3	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
6	Cofactor
2	Expression
1	General Stability
5	Inhibitors
4	KM Value [mM]
1	Metals/Ions
4	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
12	Organism
2	Pathway
2	pH Optimum
1	pH Range
2	pH Stability
2	Protein Variants
2	Purification (Commentary)
1	Reaction
2	Reaction Type
9	Reference
4	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
29	Substrates and Products (Substrate)
4	Subunits
9	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Turnover Number [1/s]

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Reference on EC 1.14.13.63 - 3-hydroxyphenylacetate 6-hydroxylase

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7425

van Berkel, W.J.H.; van den Tweel, W.J.J.

Purification and characterisation of 3-hydroxyphenylacetate 6-hydroxylase: a novel FAD-dependent monooxygenase from a Flavobacterium species

Eur. J. Biochem.

201

585-591

1991

Flavobacterium sp., Flavobacterium sp. JS-7

1935954

7426

Van den Tweel, W.J.J.; Smits, J.P.; de Bont, J.A.M.

Catabolism of DL-alpha-phenylhydracrylic, phenylacetic and 3- and 4-hydroxyphenylacetic acid via homogentisic acid in a Flavobacterium sp.

Arch. Microbiol.

149

207-213

1988

Flavobacterium sp.

659614

Suemori, A.; Nakajima, K.; Kurane, R.; Nakamura, Y.

Purification and characterization of o-hydroxyphenylacetate 5-hydroxylase, m-hydroxyphenylacetate 6-hydroxylase and p-hydroxyphenylacetate 1-hydroxylase from Rhodococcus erythropolis

J. Ferment. Bioeng.

133-137

1996

Rhodococcus erythropolis, Rhodococcus erythropolis S1

673422

Ferrer-Sevillano, F.; Fernandez-Canon, J.M.

Novel phacB-encoded cytochrome P450 monooxygenase from Aspergillus nidulans with 3-hydroxyphenylacetate 6-hydroxylase and 3,4-dihydroxyphenylacetate 6-hydroxylase activities

Eukaryot. Cell

514-520

2007

Aspergillus nidulans (Q078T0), Aspergillus nidulans, Aspergillus nidulans BiA1 (Q078T0)

17189487

745063

Sartori, D.; Massi, F.P.; Ferranti, L.S.; Fungaro, M.H.

Identification of genes differentially expressed between Ochratoxin-producing and non-producing strains of Aspergillus westerdijkiae

Indian J. Microbiol.

41-45

2014

Aspergillus westerdijkiae (E2EB14), Aspergillus westerdijkiae UEL91 (E2EB14)

24426165