1.14.13.38: anhydrotetracycline 6-monooxygenase

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For detailed information about anhydrotetracycline 6-monooxygenase, go to the full flat file.

Reaction

Synonyms

anhydrotetracycline hydroxylase, anhydrotetracycline monooxygenase, anhydrotetracycline oxygenase, ATC oxygenase, oxygenase, anhydrotetracycline, oxyS

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.38 anhydrotetracycline 6-monooxygenase

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Results	in table
1	Activating Compound
127	AA Sequence
3	Application
1	CAS Registry Number
2	Cloned(Commentary)
7	Cofactor
1	General Stability
14	Inhibitors
1	KM Value [mM]
7	Localization
9	Metals/Ions
3	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
12	Organism
5	Pathway
3	pH Optimum
2	Protein Variants
3	Purification (Commentary)
1	Reaction
3	Reaction Type
12	Reference
5	Specific Activity [micromol/min/mg]
2	Storage Stability
13	Substrates and Products (Substrate)
2	Subunits
7	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Specific Activity

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Specific Activity on EC 1.14.13.38 - anhydrotetracycline 6-monooxygenase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.0000112

Streptomyces rimosus

Q58PK7

recombinant wild-type enzyme in Escherichia coli cell extract

674496

0.00264

Kitasatospora aureofaciens

-

low production strain, membrane fraction

438863

0.0078

Kitasatospora aureofaciens

-

high production strain, cytoplasm

438863

0.44

Kitasatospora aureofaciens

-

-

438861

additional information

Kitasatospora aureofaciens

-

overview: different activities in various subcellular fractions

438863