1.14.13.27: 4-aminobenzoate 1-monooxygenase
This is an abbreviated version!
For detailed information about 4-aminobenzoate 1-monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.27
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1.14.13.27
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agaricus
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bisporus
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mushroom
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fad-binding
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edible
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fad
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fad-dependent
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glycylglycine
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gamma-glutamyltransferase
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tsuji
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apoenzyme
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epitopes
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salicylate
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ogawa
- 1.14.13.27
-
agaricus
- bisporus
- mushroom
-
fad-binding
-
edible
- fad
-
fad-dependent
- glycylglycine
- gamma-glutamyltransferase
-
tsuji
-
apoenzyme
- epitopes
- salicylate
-
ogawa
Reaction
Synonyms
4-aminobenzoate hydroxylase, oxygenase, 4-aminobenzoate mono-
ECTree
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Substrates Products
Substrates Products on EC 1.14.13.27 - 4-aminobenzoate 1-monooxygenase
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REACTION DIAGRAM
2-amino-5-chlorobenzoate + NAD(P)H + O2
4-chloro-2-hydroxyaniline + NAD(P)+ + H2O2 + CO2
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H2O2 formed simultaneously with hydroxylation
?
3,4-diaminobenzoate + NAD(P)H + O2
2-amino-4-hydroxyaniline + NAD(P)+ + H2O2 + CO2
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17.3% of the reaction with 4-aminobenzoate
H2O2 formed simultaneously with hydroxylation
?
3-chloro-4-aminobenzoate + NAD(P)H + H+ + O2
2-chloro-4-hydroxyaniline + NAD(P)+ + H2O + CO2
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-
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?
4-amino-2-chlorobenzoate + NAD(P)H + O2
3-chloro-4-hydroxyaniline + NAD(P)+ + H2O2 + CO2
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-
H2O2 formed simultaneously with hydroxylation
?
4-aminobenzoate + NADH + H+ + O2
4-hydroxyaniline + NAD+ + H2O + CO2
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r
4-hydroxybenzoate + NAD(P)H + O2
quinol + NAD(P)+ + H2O2 + CO2
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8.4% of the reaction with 4-aminobenzoate
H2O2 formed simultaneously with hydroxylation
?
4-hydroxyaniline + NAD(P)+ + H2O + CO2
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-
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?
4-aminobenzoate + NAD(P)H + O2
4-hydroxyaniline + NAD(P)+ + H2O + CO2
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-
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?
4-aminobenzoate + NAD(P)H + O2
4-hydroxyaniline + NAD(P)+ + H2O + CO2
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?
4-aminobenzoate + NAD(P)H + O2
4-hydroxyaniline + NAD(P)+ + H2O + CO2
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?
3,4-dihydroxyaniline + NAD(P)+ + H2O2 + CO2
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?
4-aminosalicylate + NAD(P)H + O2
3,4-dihydroxyaniline + NAD(P)+ + H2O2 + CO2
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H2O2 formed simultaneously with hydroxylation
?
2-hydroxyaniline + NAD(P)+ + H2O2 + CO2
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?
anthranilate + NAD(P)H + O2
2-hydroxyaniline + NAD(P)+ + H2O2 + CO2
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H2O2 formed simultaneously with hydroxylation
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additional information
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several aromatic compounds stimulate NADH oxidation, but no hydroxylated product is formed, all of the O2 consumed is converted to H2O2
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