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1.14.13.182: 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

This is an abbreviated version!
For detailed information about 2-heptyl-3-hydroxy-4(1H)-quinolone synthase, go to the full flat file.

Reaction

2-heptyl-4(1H)-quinolone
+
NADH
+
H+
+
O2
=
2-heptyl-3-hydroxy-4(1H)-quinolone
+
NAD+
+
H2O

Synonyms

2-heptyl-3,4-dihydroxyquinoline synthase, Aqm, PqsH

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

Cofactor

Cofactor on EC 1.14.13.182 - 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADH
kcat/KM for NADH is 20fold higher than kcat/Km for NADPH
NADPH
kcat/KM for NADH is 20fold higher than kcat/Km for NADPH
riboflavin
flavin-dependent monooxygenase, riboflavin is included in the assay