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1.14.13.178: methylxanthine N1-demethylase

This is an abbreviated version!
For detailed information about methylxanthine N1-demethylase, go to the full flat file.

Reaction

Caffeine
+
O2
+
NAD(P)H
+
H+
=
Theobromine
+
NAD(P)+
+
H2O
+
formaldehyde

Synonyms

ndmA, P450-d

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.178 methylxanthine N1-demethylase

KM Value

KM Value on EC 1.14.13.178 - methylxanthine N1-demethylase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.27
1-Methylxanthine
pH 7.5, 30°C
0.037
Caffeine
pH 7.5, 30°C
0.053
paraxanthine
pH 7.5, 30°C
0.0091
theophylline
pH 7.5, 30°C