1.14.12.11: toluene dioxygenase

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For detailed information about toluene dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.11

1.14.12.11

putida

naphthalene

trichloroethylene

ethylbenzene

chlorobenzene

cis-dihydrodiols

dihydrodiols

cis-dihydroxylation

dot-t1e

ring-hydroxylating

cis-toluene

indene

cis-diols

pseudoalcaligenes

1-indanone

toluene-grown

3-methylcatechol

synthesis

analysis

degradation

Reaction

(1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol

Synonyms

ISPTOD, ISPTOL, More, oxygenase, toluene 2,3-di-, oxygenaseTOL, TDO, Tod, todC1C2BA, toluene 2,3-dioxygenase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor

1.14.12.11 toluene dioxygenase

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Results	in table
14	AA Sequence
8	Application
1	CAS Registry Number
20	Cloned(Commentary)
52	Cofactor
2	Crystallization (Commentary)
1	Expression
7	General Information
4	Inhibitors
2	KM Value [mM]
8	Metals/Ions
15	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
210	Organism
7	Pathway
4	PDB ID
1	pH Optimum
1	pI Value
1	Posttranslational Modification
15	Protein Variants
12	Purification (Commentary)
3	Reaction
4	Reaction Type
85	Reference
1	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
318	Substrates and Products (Substrate)
11	Subunits
40	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.14.12.11 - toluene dioxygenase

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toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase, and a ferredoxin. Some other aromatic compounds, including ethylbenzene, 4-xylene and some halogenated toluenes, are converted into the corresponding cis-dihydrodiols.