1.14.11.53: mRNA N6-methyladenine demethylase

This is an abbreviated version, for detailed information about mRNA N6-methyladenine demethylase, go to the full flat file.

Reaction

N6-methyladenine in mRNA
+
2-oxoglutarate
+
O2
=
adenine in mRNA
+
formaldehyde
+
succinate
+
CO2

Synonyms

AlkB homolog 5, ALKBH5, ALKBH5 demethylase, fat mass and obesity-associated protein, FTO, m6A RNA demethylase, m6A-RNA demethylase, RNA N6-methyladenine demethylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.53 mRNA N6-methyladenine demethylase