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1.14.11.52: validamycin A dioxygenase

This is an abbreviated version!
For detailed information about validamycin A dioxygenase, go to the full flat file.

Reaction

validamycin A
+
2-oxoglutarate
+
O2
=
validamycin B
+
succinate
+
CO2

Synonyms

VldW

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.52 validamycin A dioxygenase

Inhibitors

Inhibitors on EC 1.14.11.52 - validamycin A dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ni2+
atalytic activity is affected by Ni2+. A significant reduction of activity is observed when the protein is purified using Ni-NTA column. The activity can be restored by dialysis of the protein in a buffer solution containing 0.1 mM EDTA, followed by the addition of 0.2 mM of Fe2+ to the protein solution