1.14.11.49: uridine-5'-phosphate dioxygenase
This is an abbreviated version!
For detailed information about uridine-5'-phosphate dioxygenase, go to the full flat file.
Word Map on EC 1.14.11.49
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1.14.11.49
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huntington
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chorionic
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estriol
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somatomammotropin
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high-content
- 1.14.11.49
-
huntington
-
chorionic
- estriol
-
somatomammotropin
-
high-content
Reaction
Synonyms
alpha-ketoglutarate:UMP dioxygenase, alpha-KG:UMP dioxygenase, LIPL, UMP:alpha-ketoglutarate dioxygenase, uridine-5-monophosphate alpha-ketoglutarate dioxygenase
ECTree
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Systematic Name
Systematic Name on EC 1.14.11.49 - uridine-5'-phosphate dioxygenase
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UMP,2-oxoglutarate:oxygen oxidoreductase
The enzyme catalyses a net dephosphorylation and oxidation of UMP to generate 5'-dehydrouridine, the first intermediate in the biosynthesis of the unusual aminoribosyl moiety found in several C7-furanosyl nucleosides such as A-90289s, caprazamycins, liposidomycins, muraymycins and FR-900453. Requires Fe2+.