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1.14.11.45: L-isoleucine 4-hydroxylase

This is an abbreviated version!
For detailed information about L-isoleucine 4-hydroxylase, go to the full flat file.

Word Map on EC 1.14.11.45

Reaction

L-isoleucine
+
2-oxoglutarate
+
O2
=
(4S)-4-hydroxy-L-isoleucine
+
succinate
+
CO2

Synonyms

IDO, isoleucine 4-hydroxylase, L-isoleucine dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.45 L-isoleucine 4-hydroxylase

pH Stability

pH Stability on EC 1.14.11.45 - L-isoleucine 4-hydroxylase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 8
-
the enzyme remains stable between pH 5.0 and 8.0 for 24 h
741745
7 - 9
-
the enzyme retains over 90% activity after 1 h of incubation at pH 7.0-9.0
730987