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1.14.11.44: (R)-dichlorprop dioxygenase (2-oxoglutarate)

This is an abbreviated version!
For detailed information about (R)-dichlorprop dioxygenase (2-oxoglutarate), go to the full flat file.

Word Map on EC 1.14.11.44

Reaction

(R)-(2,4-dichlorophenoxy)propanoate
+
2-oxoglutarate
+
O2
=
2,4-Dichlorophenol
+
pyruvate
+
succinate
+
CO2

Synonyms

(R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-oxoglutarate-dependent (R)-dichlorprop dioxygenase, AAD-1, alpha-ketoglutarate-dependent (R)-dichlorprop dioxygenase, ariloxyalkanoate-dioxygenase-1, RdpA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.44 (R)-dichlorprop dioxygenase (2-oxoglutarate)

Substrates Products

Substrates Products on EC 1.14.11.44 - (R)-dichlorprop dioxygenase (2-oxoglutarate)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2
2,4-dichlorophenol + pyruvate + succinate + CO2
show the reaction diagram
(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2
4-chloro-2-methylphenol + pyruvate + succinate + CO2
show the reaction diagram
additional information
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construction of homology models of SdpA and RdpA from Sphingomonas herbicidovorans MH and the use of docking to identify residues likely to be involved in herbicide binding
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