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1.14.11.32: codeine 3-O-demethylase

This is an abbreviated version!
For detailed information about codeine 3-O-demethylase, go to the full flat file.

Word Map on EC 1.14.11.32

Reaction

codeine
+
2-oxoglutarate
+
O2
=
morphine
+
formaldehyde
+
succinate
+
CO2

Synonyms

codeine O-demethylase, codeine-O-demethylase, CODM

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.32 codeine 3-O-demethylase

KM Value

KM Value on EC 1.14.11.32 - codeine 3-O-demethylase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.019
2-oxoglutarate
-
pH 7.4, 30°C
0.0205 - 0.0728
codeine
0.0419 - 0.216
thebaine
additional information
additional information
-
steady-state enzyme kinetics of purified recombinant CODM using (S)-scoulerine as substrate
-