1.14.11.2: procollagen-proline 4-dioxygenase

This is an abbreviated version!
For detailed information about procollagen-proline 4-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.2

1.14.11.2

anemia

fibrosis

procollagens

endothelial

erythropoietin

hydroxylases

tetramer

hemoglobin

lysyl

beta-subunits

oxygen-dependent

4-hydroxyproline

ascorbate

roxadustat

normoxia

hippel-lindau

alpha-subunits

erythropoiesis-stimulating

hepcidin

myofibroblasts

dmog

hif-alpha

oxygen-sensing

glucosyltransferase

fibroblast-like

alpha-smooth

hif-prolyl

erythrocytosis

triple-helical

collagen-like

hif-dependent

4-hydroxylation

alpha2beta2

treatment-emergent

alphai

hypoxia-responsive

3,4-dihydroxybenzoate

3-hydroxylase

2-oxoglutarate-dependent

hippel

dimethyloxalylglycine

darbepoetin

non-dialysis-dependent

asparaginyl

medicine

hif-mediated

diagnostics

analysis

nutrition

drug development

Reaction

Synonyms

A085R, alpha (I) subunit, anthrax-P4H, AT-P4H-1, At-P4H-2, BaP4H, C-P4H, C-P4H alpha subunit (III), C-P4H alpha(I), C-P4H alpha(III), CePHY-1/PHY-2/PDI2, collagen proline hydroxylase, collagen prolyl 4-hydroxylase, collagen prolyl 4-hydroxylase (type-II), collagen prolyl 4-hydroxylase 1, collagen prolyl-4-hydroxylase, collagen prolyl-4-hydroxylase alpha subunit 2, CP4H, CP4H1, CrP4H-1, DmP4H, egg-laying abnormal-9 prolyl hydroxylase, Egl nine homolog, EGLN, EGLN prolyl hydroxylase, EGLN3, EGLN3 hydroxylase, GBAA_4459, HIF prolyl hydroxylase, HIF prolyl-4-hydroxylase, HIF-1alpha-specific prolyl-hydroxylase, HIF-P4H-1, HIF-P4H-2, HIF-P4H-3, HPH, HPH-2, HuPH4-I, HuPH4-II, hydroxylase, collagen proline, hypoxia inducible factor prolyl-4-hydroxylase domain-containing protein, hypoxia inducible factor-prolyl hydroxylase, hypoxia-inducible factor -1alpha-type prolyl 4-hydroxylase, hypoxia-inducible factor prolyl hydroxylase, hypoxia-inducible factor-1alpha-prolyl-hydroxylase 2, More, NtP4H1.1, P4H, P4H alpha1, P4H-1, P4H1, P4ha1, P4ha2, P4Halpha(I), P4Halpha(II), P4Halpha(III), P4Halpha1, PBCV-1 P4H, peptidyl proline hydroxylase, PH, PHD, PHD-1, PHD1, PHD2, PHD3, procollagen prolyl 4-hydroxylase, procollagen-proline dioxygenase, proline 4-hydroxylase, proline hydroxylase, proline protocollagen hydroxylase, proline, 2-oxoglutarate dioxygenase, proline,2-oxoglutarate 4-dioxygenase, prolyl 4-hydroxylase, prolyl 4-hydroxylase A085R, prolyl hydroxylase, prolyl hydroxylase domain 1, prolyl hydroxylase domain containing protein, prolyl hydroxylase domain enzyme, prolyl hydroxylase domain protein 2, prolyl hydroxylase-1, prolyl hydroxylase-3, prolyl-4-hydroxylase, prolyl-4-hydroxylase alpha I, prolyl-4-hydroxylase alpha II, prolyl-4-hydroxylase alpha subunit 2, prolyl-4-hydroxylase alpha1, prolyl-4-hydroxylase-alpha1, prolyl-4-hydroxylases, prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating, prolyl4-hydroxylase, prolylprotocollagen dioxygenase, prolylprotocollagen hydroxylase, protocollagen hydroxylase, protocollagen proline 4-hydroxylase, protocollagen proline dioxygenase, protocollagen proline hydroxylase, protocollagen prolyl hydroxylase, PSB-II, Skp1 prolyl hydroxylase, type I C-P4H, type I proly 4-hydroxylase, type I proyl 4-hydroxylase, type II proyl 4-hydroxylase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

1.14.11.2 procollagen-proline 4-dioxygenase

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Results	in table
151	Activating Compound
7207	AA Sequence
14	Application
1	CAS Registry Number
57	Cloned(Commentary)
116	Cofactor
11	Crystallization (Commentary)
1673	Disease/ Diagnostics
12	Expression
59	General Information
8	General Stability
2	IC50 Value
420	Inhibitors
4	kcat/KM [mM/s]
191	Ki Value [mM]
281	KM Value [mM]
40	Localization
114	Metals/Ions
62	Molecular Weight [Da]
66	Natural Substrates/ Products (Substrates)
708	Organism
3	Pathway
23	PDB ID
31	pH Optimum
2	pH Stability
1	pI Value
17	Posttranslational Modification
82	Protein Variants
74	Purification (Commentary)
15	Reaction
5	Reaction Type
209	Reference
1	Renatured (Commentary)
227	Source Tissue
52	Specific Activity [micromol/min/mg]
8	Storage Stability
404	Substrates and Products (Substrate)
97	Subunits
226	Synonyms
1	Systematic Name
46	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
44	Turnover Number [1/s]

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Synonyms on EC 1.14.11.2 - procollagen-proline 4-dioxygenase

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A085R

Paramecium bursaria Chlorella virus 1

Q84406

765717

alpha (I) subunit