1.13.99.3: tryptophan 2'-dioxygenase

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For detailed information about tryptophan 2'-dioxygenase, go to the full flat file.

Reaction

Synonyms

indole-3-alkane alpha-hydroxylase, indolyl-3-alkane alpha-hydroxylase, oxidase, tryptophan side-chain alpha,beta-, oxidase, tryptophan side-chain alpha,beta-, II, tryptophan side chain oxidase, tryptophan side chain oxidase II, tryptophan side chain oxidase type I, tryptophan side-chain alpha,beta-oxidase, tryptophan side-chain oxidase, TSO, TSO I, TSO II, TSOII

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.99 Miscellaneous

                1.13.99.3 tryptophan 2'-dioxygenase

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2	Activating Compound
1	Application
2	CAS Registry Number
10	Cofactor
2	Crystallization (Commentary)
5	Disease/ Diagnostics
1	General Information
15	Inhibitors
17	KM Value [mM]
4	Metals/Ions
14	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
16	Organism
5	Pathway
4	pH Optimum
6	pH Stability
1	pI Value
2	Protein Variants
4	Purification (Commentary)
4	Reaction
3	Reaction Type
16	Reference
4	Specific Activity [micromol/min/mg]
3	Storage Stability
74	Substrates and Products (Substrate)
6	Subunits
14	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
3	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.13.99.3 - tryptophan 2'-dioxygenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

L-tryptophan + O2

(indol-3-yl)glycolaldehyde + CO2 + NH3

Pseudomonas sp. ATCC 29574

-

-

764917

-

-

?

L-tryptophan + O2

3-indoleglycolaldehyde + CO2 + NH3

Pseudomonas fluorescens

-

first enzyme of metabolic pathway for tryptophan

439304, 439308

-

-

?