1.13.12.5: Renilla-type luciferase

This is an abbreviated version!
For detailed information about Renilla-type luciferase, go to the full flat file.

Word Map on EC 1.13.12.5

1.13.12.5

bioluminescence

luminescence

photoproteins

firefly

agonist

ventricular

contractile

tension

ferret

emit

twitch

isometric

papillary

depolarization

ca2+-sensitive

microinjected

myocardium

sarcoplasmic

aequorea

caffeine

ryanodine

myofilaments

inotropic

jellyfish

calcium-sensitive

luciferases

victoria

excitation-contraction

fura-2

replicons

ca2+cyt

tetanic

light-emitting

analysis

glow

trabeculae

insp3

biotechnology

photinus

signal-to-background

ca2+-regulated

ca2+-triggered

barnacle

luminometer

luminescence-based

myoplasmic

ca2+-mobilizing

molecular biology

diagnostics

pharmacology

isovolumic

charge-coupled

luciferase-based

pyralis

photomultiplier

Reaction

Synonyms

19kOLase, aequorin, aequorin-1, BFP-aq, blue fluorescent protein from the calcium-binding photoprotein aequorin, Caussia princeps luciferase, clytin, extGLuc, extRLuc, firefly luciferase, fluc, Gaussia luciferase, Gaussia luciferase enzyme, Gaussia princeps luciferase, Gaussia-luciferase, GFP-aq, GLase, GLuc, Luc, luciferase, luciferase (Renilla luciferin), m-Rluc8, membrane-anchored RLUc, Oplophorus luciferase, PI-Rluc, R-Luc, Renilla luciferase, Renilla luciferase-547, Renilla luciferin 2-monooxygenase, Renilla muelleri luciferase, Renilla reniformis luciferase, Renilla-luciferase, Renilla-luciferin 2-monooxygenase, Renilla-type luciferase, RLase, RLase-547, RLuc, RLuc8, short peptide-inserted-Renilla luciferase

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

1.13.12.5 Renilla-type luciferase

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Results	in table
14	Activating Compound
18	AA Sequence
35	Application
2	CAS Registry Number
42	Cloned(Commentary)
4	Crystallization (Commentary)
8	General Information
1	General Stability
24	IC50 Value
97	Inhibitors
4	Ki Value [mM]
19	KM Value [mM]
14	Localization
13	Metals/Ions
24	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
78	Organism
1	Oxidation Stability
16	PDB ID
21	pH Optimum
1	pH Range
2	pH Stability
5	Posttranslational Modification
137	Protein Variants
26	Purification (Commentary)
7	Reaction
6	Reaction Type
78	Reference
17	Specific Activity [micromol/min/mg]
2	Storage Stability
138	Substrates and Products (Substrate)
16	Subunits
99	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
5	Temperature Range [°C]
27	Temperature Stability [°C]
8	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.13.12.5 - Renilla-type luciferase

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0.05

(2Z)-3-[(2-bromophenyl)amino]-1-pyridin-2-ylprop-2-en-1-one

Renilla reniformis

IC50 above 0.05 mM

688275

0.011

(2Z)-3-[[4-(dimethylamino)cyclohexa-1,5-dien-1-yl]amino]-1-phenylprop-2-en-1-one

2 entries

0.019

(3Z)-3-[[4-(dimethylamino)phenyl]methylidene]-1,3-dihydro-2H-indol-2-one

2 entries

0.025

2-(4-ethoxyphenyl)-4-[(4-methylpiperazin-1-yl)carbonyl]quinoline

Renilla reniformis

IC50 above 0.025 mM

688275

0.011

2-(4-ethoxyphenyl)-4-[(4-pyridin-2-ylpiperazin-1-yl)carbonyl]quinoline

2 entries

0.025

2-(4-methylphenyl)-4-[(4-pyrimidin-2-ylpiperazin-1-yl)carbonyl]quinoline

Renilla reniformis

IC50 above 0.025 mM

688275

0.025

2-(5-naphthalen-2-yl-1,2,4-oxadiazol-3-yl)pyridine

2 entries

0.02

2-hydroxy-N'-[(1E)-(2-hydroxyphenyl)methylidene]benzohydrazide

2 entries

0.05

2-[5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine

Renilla reniformis

IC50 above 0.05 mM

688275

0.011

4-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(4-ethoxyphenyl)quinoline

2 entries

0.01

4-amino-6-[(E)-[4'-[(Z)-(8-amino-1-hydroxy-5,7-disulfonato-6,7-dihydronaphthalen-2-yl)diazenyl]-3-methylbiphenyl-4-yl]diazenyl]-5-hydroxy-2,3-dihydronaphthalene-1,3-disulfonate

Renilla reniformis

688275

0.0225

4-[1-(1,3-benzothiazol-2-yl)-2-(4-methylpiperazin-1-yl)-2-oxoethyl]phenol

2 entries

0.036

6-methyl-2-[(Z)-phenyldiazenyl]pyridin-3-ol

Renilla reniformis

688275

0.02

ethyl 4-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonyl]piperazine-1-carboxylate

2 entries

0.021

H-89

Renilla sp.

10 microM coelenterazine, measured RLuc8 activity

700904

0.05

N'-(3-chlorophenyl)-N-[(1Z)-(3-chlorophenyl)methylidene]imidoformamide

Renilla reniformis

IC50 above 0.05 mM

688275