1.13.12.2: lysine 2-monooxygenase
This is an abbreviated version!
For detailed information about lysine 2-monooxygenase, go to the full flat file.
Word Map on EC 1.13.12.2
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1.13.12.2
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putida
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5-aminovalerate
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glutarate
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fed-batch
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nylon
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synthesis
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fluorescens
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semialdehyde
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1,5-pentanediol
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polyamides
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glutamicum
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flavoproteins
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corynebacterium
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l-pipecolate
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biotechnology
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4-aminobutyrate
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five-carbon
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amidohydrolase
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his6-tagged
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cadaverine
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biomass
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transaminase
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permease
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byproduct
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deamination
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putrescine
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bio-based
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feedstock
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codon-optimized
- 1.13.12.2
- putida
- 5-aminovalerate
- glutarate
-
fed-batch
-
nylon
- synthesis
- fluorescens
- semialdehyde
- 1,5-pentanediol
- polyamides
- glutamicum
- flavoproteins
-
corynebacterium
- l-pipecolate
- biotechnology
- 4-aminobutyrate
-
five-carbon
-
amidohydrolase
-
his6-tagged
- cadaverine
- biomass
- transaminase
-
permease
-
byproduct
-
deamination
- putrescine
-
bio-based
-
feedstock
-
codon-optimized
Reaction
Synonyms
davB, L-AAO/MOG, L-amino acid oxidase/monooxygenase, L-LOX/MOG, L-lysine 2-monooxygenase, L-lysine monooxygenase, L-lysine oxidase/monooxygenase, L-lysine-2-monooxygenase, lysine monooxygenase, lysine oxygenase
ECTree
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Inhibitors
Inhibitors on EC 1.13.12.2 - lysine 2-monooxygenase
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4-Methyllysine
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at higher substrate concentrations, competitive inhibitor
5-Methyllysine
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at higher substrate concentrations, competitive inhibitor
alkylamines
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high concentration inhibits, low concentrations stimulate lysine oxygenation
Nepsilon-Methyllysine
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at higher substrate concentrations, competitive inhibitor
ornithine
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at low concentration of L-lysine reaction is stimulated by L-ornithine, at high concentrations of L-lysine it is inhibited
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increases oxidase and dehydrogenase activities, decreases oxygenase activity
p-chloromercuribenzoate
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conversion of oxygenase to oxidase; increases oxidase and dehydrogenase activities, decreases oxygenase activity
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alkylating and oxidizing reagents convert oxygenase to oxidase; various sulfhydryl reagents including certain mercurials
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additional information
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at low lysine concentrations, inhibition by a variety of buffers
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additional information
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alkylating and oxidizing reagents convert oxygenase to oxidase
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additional information
4-chloromercuribenzoate inhibits only the oxidase activity of the bifunctional enzyme, while the monooxygenase activity is not affected
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