1.13.12.16: nitronate monooxygenase
This is an abbreviated version!
For detailed information about nitronate monooxygenase, go to the full flat file.
Word Map on EC 1.13.12.16
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1.13.12.16
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nitroalkanes
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flavin
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nitroethane
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neurospora
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crassa
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fmn
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hansenula
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mrakii
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flavosemiquinone
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1-nitropropane
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denitrification
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3-nitropropionic
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ansochromogenes
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fmn-dependent
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saturnus
- 1.13.12.16
- nitroalkanes
- flavin
- nitroethane
- neurospora
- crassa
- fmn
- hansenula
- mrakii
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flavosemiquinone
- 1-nitropropane
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denitrification
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3-nitropropionic
- ansochromogenes
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fmn-dependent
- saturnus
Reaction
Synonyms
2-nitropropane dioxygenase, EC 1.13.11.32, NAO, ncd2, nitroalkane oxidase, nitroalkane-oxidizing enzyme, nitronate monooxygenase, nitropropane dioxygenase, NMO, NMO-Nc, NMO-Ws, nmoA, Npd1, Npd2, Npd3, Npd4, Npd5, Npd6, oxidase, nitroalkane, oxygenase, 2-nitropropane di-, P3N monooxygenase, Pa-NMO, PA4202, protein PA4202, Rv1894c, Sa-NAO
ECTree
1.13.12.16 nitronate monooxygenaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 1.13.12.16 - nitronate monooxygenase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3 propionate-3-nitronate + O2
3 malonic semialdehyde + nitrite + 2 nitrate + H2O2
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?
ethylnitronate + O2
acetaldehyde + nitrite + other products
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?
ethylnitronate + O2 + FMNH2
acetaldehyde + nitrite + FMN + H2O
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?
ethylnitronate + O2 + FMNH2
acetaldehyde + nitrite + FMN + H2O
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?
ethylnitronate + O2 + FMNH2
acetaldehyde + nitrite + FMN + H2O
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?
propyl-2-nitronate + O2 + FMNH2
? + nitrite + FMN + H2O
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?
additional information
?
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enzyme catalyzes the oxygenative denitrification of anionic nitroalkanes much more effectively than that of the neutral ones
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?
additional information
?
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enzyme catalyzes the oxygenative denitrification of anionic nitroalkanes much more effectively than that of the neutral ones
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?
additional information
?
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only alkyl nitronates are used as substrates in the oxidative denitrification reaction catalyzed by Williopsis saturnus var. mrakii NMO, nitroalkanes are no substrates. The different substrate specificity compared to other NMOs might result from the presence of a His residue in the active site and conformational differences. NMO does not produce and release hydrogen peroxide during turnover with linear alkyl nitronates of various lengths between 2 and 6 carbon atoms or with propyl-2-nitronate. With the exception of propyl-2-nitronate, there is no release of superoxide during turnover of NMO at pH 8.0 and 30°C with linear alkyl nitronates with chain lengths between 2 and 6 carbon atoms
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?
additional information
?
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only alkyl nitronates are used as substrates in the oxidative denitrification reaction catalyzed by Williopsis saturnus var. mrakii NMO, nitroalkanes are no substrates. The different substrate specificity compared to other NMOs might result from the presence of a His residue in the active site and conformational differences. NMO does not produce and release hydrogen peroxide during turnover with linear alkyl nitronates of various lengths between 2 and 6 carbon atoms or with propyl-2-nitronate. With the exception of propyl-2-nitronate, there is no release of superoxide during turnover of NMO at pH 8.0 and 30°C with linear alkyl nitronates with chain lengths between 2 and 6 carbon atoms
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?
additional information
?
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active on primary and secondary nitroalkanes, with a marked preference for unbranched primary nitroalkanes
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?
additional information
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enzyme is more specific for nitronates than nitroalkanes
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?
additional information
?
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enzyme is more specific for nitronates than nitroalkanes
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?
additional information
?
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both the neutral and anionic forms of nitroalkanes act as substrates for the oxidative denitrification reaction catalyzed by Neurospora crassa NMO. NMO does not produce and release hydrogen peroxide during turnover with linear alkyl nitronates of various lengths between 2 and 6 carbon atoms or with propyl-2-nitronate. With the exception of propyl-1- and propyl-2-nitronate, there is no release of superoxide during turnover of NMO at pH 8.0 and 30°C with linear alkyl nitronates with chain lengths between 2 and 6 carbon atoms
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?
