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1.13.11.53: acireductone dioxygenase (Ni2+-requiring)

This is an abbreviated version!
For detailed information about acireductone dioxygenase (Ni2+-requiring), go to the full flat file.

Word Map on EC 1.13.11.53

Reaction

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one
+
O2
=
3-(methylsulfanyl)propanoate
 +
formate
 +
CO

Synonyms

2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase, aci-reductone dioxygenase, acidoreductone dioxygenase, acireductone dioxygenase, acireductone dioxygenase 1, ADI1, ARD, ARD1, human aci-reductone dioxygenase 1, membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1, MTCBP1, MtnD, Ni(II)-ARD, Ni(II)-bound acireductone dioxygenase, Ni-ARD, nickel acireductone dioxyegenase, nickel acireductone dioxygenase, Sip-L

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.53 acireductone dioxygenase (Ni2+-requiring)

Disease

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Disease on EC 1.13.11.53 - acireductone dioxygenase (Ni2+-requiring)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinogenesis
Human acireductone dioxygenase (HsARD), cancer and human health: Black hat, white hat or gray?
Carcinoma
Human acireductone dioxygenase (HsARD), cancer and human health: Black hat, white hat or gray?
Carcinoma, Hepatocellular
Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L.
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
Hepatitis C
dBMHCC: A comprehensive hepatocellular carcinoma (HCC) biomarker database provides a reliable prediction system for novel HCC phosphorylated biomarkers.
Emergence of mutation clusters in the HCV genome during sequential viral passages in Sip-L expressing cells.
Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L.
Interaction between hepatic membrane type 1 matrix metalloproteinase and acireductone dioxygenase 1 regulates hepatitis C virus infection.
Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.
Infections
Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L.
Neoplasms
Human acireductone dioxygenase (HsARD), cancer and human health: Black hat, white hat or gray?
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
Prostatic Neoplasms
Expression and function of the human androgen-responsive gene ADI1 in prostate cancer.
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
Virus Diseases
dBMHCC: A comprehensive hepatocellular carcinoma (HCC) biomarker database provides a reliable prediction system for novel HCC phosphorylated biomarkers.
Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L.
Interaction between hepatic membrane type 1 matrix metalloproteinase and acireductone dioxygenase 1 regulates hepatitis C virus infection.