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1.13.11.51: 9-cis-epoxycarotenoid dioxygenase

This is an abbreviated version!
For detailed information about 9-cis-epoxycarotenoid dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.51

Reaction

9'-cis-neoxanthin
+
O2
=
2-cis,4-trans-xanthoxin
 +
(3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al

Synonyms

9,10[9',10']carotenoid cleavage dioxygenase, 9-cis epoxycarotenoid dioxygenase, 9-cis-epoxcarotenoid dioxygenase, 9-cis-epoxicarotenoid dioxygenase, 9-cis-epoxycarotenoid dioxygenase, 9-cis-epoxycarotenoid dioxygenase 3, 9-cis-epoxycarotenoid dioxygenase 4, 9-cis-epoxycarotenoid dioxygenase 6, 9-cis-epoxycarotenoid dioxygenase1, 9-cis-epoxycarotenoid dioxygenase4, AtCCD1, AtNCED3, B-diox-II, carotenoid cleavage dioxygenase, carotenoid cleavage dioxygenase 1, CCD, CCD1, CCD7, CCD8, CitNCED2, CitNCED3, CMNCED1, CsNCED1, CsNCED2, DHN2, DKNCED1, LeNCED1, LeNCED2, LsNCED1, LsNCED2, LsNCED3, LsNCED4, NCED, NCED 3, NCED1, NCED2, NCED2A, NCED2B, NCED2D, NCED3, NCED3a, NCED4, NCED5, NCED6, NCED9, nine-cis-epoxy dioxygenase, nine-cis-epoxycarotenoid dioxygenase, nine-cis-epoxycarotenoid dioxygenase 3, NosCCD, Nostoc carotenoid cleavage dioxygenase, NSC1, NSC2, NSC3, PpNCED1, PpNCED2, putative carotenoid cleavage dioxygenase, PvNCED1, SgNCED1, STO1, VP14, VP14 epoxy-carotenoid dioxygenase, VP14 protein, VuNCED1 protein, VvNCED1

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.51 9-cis-epoxycarotenoid dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.51 - 9-cis-epoxycarotenoid dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(1R,3S,6R)-(3'Z)-1,5,5-trimethyl-6-(3'-methyl-5'-(phenylamino)-pent-3'-en-1'-ynyl)-7-oxabicyclo[4.1.0]heptan-3-ol
-
1 mM, complete inhibition of enzyme activity
(1R,3S,6R)-(3'Z)-1,5,5-trimethyl-6-(3'-methyl-5'-(phenylthio)-pent-3'-en-1'-ynyl)-7-oxa-bicyclo[4.1.0]heptan-3-ol
-
1 mM, complete inhibition of enzyme activity
(1R,4R,6R)-(3'Z)-1-(5'-(ethylthio)-3'-methylpent-3'-en-1'-ynyl)-2,2,6-trimethylcyclohexane-1,4-diol
-
1 mM, about 25% inhibition of enzyme activity
(1S,4R,6R)-(3'Z)-1-(5'-(ethylthio)-3'-methylpent-3'-en-1'-ynyl)-2,2,6-trimethylcyclohexane-1,4-diol
-
1 mM, about 65% inhibition of enzyme activity
(2E)-3-(3,4-dimethoxyphenyl)-N-hydroxyprop-2-enamide
-
11% inhibition at 0.1 mM
(2Z,4E)-5-(1'-hydroxy-2',2',6'-trimethyl-4'-oxocyclohexyl)-3-methylpenta-2,4-dienyl 2-(thiophen-2''-yl)acetate
-
1 mM, about 70% inhibition of enzyme activity
(3,4-dimethoxybenzyl)[2-(4-methoxy-phenyl)-ethyl]methylamine
IC50: 0.087 mM
(4R,5S)-(3'Z)-4-(5'-(ethylthio)-3'-methylpent-3'-en-1'-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexanone
-
1 mM, complete inhibition of enzyme activity
(4S,5R)-(3'Z)-4-(5'-(ethylthio)-3'-methylpent-3'-en-1'-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexanone
-
1 mM, about 55% inhibition of enzyme activity
(4S,5R/4R,5S)-(3'Z)-4-(5'-(ethylthio)-3'-methylpent-3'-en-1'-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexanone
-
1 mM, 75% inhibition of enzyme activity
1-aminocyclopropane-1-carboxylic acid
1-methylcyclopropene
2-(1,3-benzodioxol-5-yl)-N-(4-fluorobenzyl)-N-hydroxyacetamide
-
33% inhibition at 0.1 mM
-
2-(3,4-dihydroxyphenyl)-N-(4-fluorobenzyl)-N-hydroxyacetamide
-
4% inhibition at 0.1 mM
-
2-(3,4-dimethoxyphenyl)-N-(4-fluorobenzyl)-N-hydroxyacetamide
-
18% inhibition at 0.1 mM
-
2-([[2-(4-hydroxyphenyl)ethyl]amino]methyl)phenol
IC50: 0.16 mM
abamine
abamine SG
-
1 mM, about 80% inhibition of enzyme activity
abscisic acid
fluridone
N-(4-fluorobenzyl)-N-hydroxy-2-(4-hydroxyphenyl)acetamide
-
29% inhibition at 0.1 mM
-
N-(4-fluorobenzyl)-N-hydroxy-2-(4-methoxyphenyl)acetamide
-
33% inhibition at 0.1 mM
-
N-(4-fluorobenzyl)-N-hydroxy-3-(4-methoxyphenyl)propanamide
-
24% inhibition at 0.1 mM
-
N-(4-fluorobenzyl)-N-hydroxy-N'-(4-methoxybenzyl)butanediamide
-
13% inhibition at 0.1 mM
-
N-benzyl-2-(3,4-dimethoxyphenyl)-N-hydroxyacetamide
-
8% inhibition at 0.1 mM
N-benzyl-3-(3,4-dimethoxyphenyl)-N-hydroxypropanamide
-
40% inhibition at 0.1 mM
N-benzyl-N-hydroxy-2-(4-hydroxyphenyl)acetamide
-
27% inhibition at 0.1 mM
N-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-en-1-yl]-4-methoxyaniline
IC50: 0.145 mM
nordihydroguaiaretic acid
[[(E)-3-(3,4-dimethoxy-phenyl)-allyl]-(4-fluoro-benzyl)-amino]-acetic acid methyl ester
IC50: 0.055 mM. Inhibitor of abscisic acid biosynthesis inhibits abscisic acid accumulation and stomatal closing
[[3-(3,4-dimethoxyphenyl)allyl]-(4-fluorobenzyl)amino]acetic acid methyl ester
competitive
additional information
-