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1.13.11.1: catechol 1,2-dioxygenase

This is an abbreviated version!
For detailed information about catechol 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.1

Reaction

catechol
+
O2
=
cis,cis-muconate

Synonyms

(chloro-)catechol 1,2-dioxygenase, 1,2 CTD, 1,2-CTD, 1,2-pyrocatechase, 3-chlorocatechol 1,2-dioxygenase, BC-C23O, C1,2-DO, C1,2O, C12, C12D, C12DO, C12O, cat12, CatA, catechase, catechol 1,2 dioxygenase, catechol 1,2-dioxygenase, catechol 1,2-dioxygenase type I, catechol 1,2-dioxygenase type II, catechol 1,2-oxygenase, catechol dioxygenase, catechol oxygenase, catechol-oxygen 1,2-oxidoreductase, catechol:oxygen 1,2-oxidoreductase, CD I, CD II, CD-I, CD-II, CD-III-1, CD-III-2, CDI1, CDI2, chlorocatechol 1,2-dioxygenase, clCA, extradiol dioxygenase MhpB, IsoB, putative catechol 2,3-dioxygenase, pyrocatechase, pyrocatechol 1,2-dioxygenase, TfdC

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.1 catechol 1,2-dioxygenase

pH Range

pH Range on EC 1.13.11.1 - catechol 1,2-dioxygenase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3 - 12
activity range, profile overview
4 - 8.5
-
activity range, immobilized enzyme
4.5 - 8
-
more than 50% activity between pH 4.5 and 8.0
5 - 11
-
45% of specific activity in pH range from 8-10.5
5 - 9
activity range, profile overview
5.2 - 8.6
-
-
6 - 8.5
-
the activity rapidly decreases outside this range
6 - 9
the enzyme retains at least 68.45% of its peak activity in the pH range of 6.0-9.0
6 - 9.5
-
pH 6.0: about 60% of maximal activity, pH 9.5: about 60% of maximal activity
6.5 - 10
6.89 - 7.49
differs between wild-type and mutant enzymes
7 - 11.5
Stutzerimonas stutzeri
pH 7.0: about 70% of maximal activity, pH 11.5: about 75% of maximal activity
7 - 9
-
high activity
7.8 - 8.8
-
increase of enzyme activity at pH 5.8-8.8, 29.3% decrease of enzyme activity at pH 9.4, 50% decrease of enzyme activity at pH 10.7