1.12.1.2: hydrogen dehydrogenase

This is an abbreviated version!
For detailed information about hydrogen dehydrogenase, go to the full flat file.

Reaction

Synonyms

bidirectional hydrogenase, bidirectional Ni-Fe hydrogenase, bidirectional NiFe-hydrogenase, bidirectional [NiFe] hydrogenase, dehydrogenase, hydrogen, FeHyd, H2:NAD+ oxidoreductase, H2ase, Hox, Hox hydrogenase, Hox type hydrogenase, HoxE, HoxEFUYH, HoxF, HoxFUYHI2, HoxH, HoxS, HoxU, HoxY, hydrogen-evolving enzyme, hydrogenase, Hyn, iron-hydrogenase, NAD+-reducing hydrogenase, NAD+-reducing NiFe hydrogenase, NAD+-reducing [NiFe]-hydrogenase, NAD-dependent hydrogenase, NAD-reducing hydrogenase, NADH-dependent Fe-only hydrogenase, NiFe hydrogenase, NiFe-type reversible hydrogenase, SH, soluble hydrogenase, soluble [NiFe]-hydrogenase, [FeFe] hydrogenase, [FeFe]-hydrogenase, [NiFe] H2ase, [NiFe] hydrogenase, [NiFe]-hydrogenase

ECTree

     1 Oxidoreductases

         1.12 Acting on hydrogen as donor

             1.12.1 With NAD⁺ or NADP⁺ as acceptor

                1.12.1.2 hydrogen dehydrogenase

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Results	in table
23	Activating Compound
1071	AA Sequence
5	Application
2	CAS Registry Number
8	Cloned(Commentary)
63	Cofactor
1	Crystallization (Commentary)
1	General Information
6	General Stability
30	Inhibitors
2	Ki Value [mM]
38	KM Value [mM]
35	Localization
65	Metals/Ions
25	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
647	Organism
11	Oxidation Stability
4	Pathway
8	PDB ID
22	pH Optimum
3	pH Range
5	pH Stability
1	Posttranslational Modification
40	Protein Variants
18	Purification (Commentary)
6	Reaction
3	Reaction Type
116	Reference
12	Source Tissue
61	Specific Activity [micromol/min/mg]
5	Storage Stability
261	Substrates and Products (Substrate)
31	Subunits
104	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
4	Temperature Stability [°C]
21	Turnover Number [1/s]

Synonyms

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Synonyms on EC 1.12.1.2 - hydrogen dehydrogenase

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

bidirectional hydrogenase

Synechocystis sp. PCC 6803

-

-

704766

bidirectional Ni-Fe hydrogenase

Synechocystis sp.

-

-

687403

bidirectional NiFe-hydrogenase

Synechocystis sp. PCC 6803

-

-

742858

bidirectional [NiFe] hydrogenase

Synechocystis sp.

-

-

704606

dehydrogenase, hydrogen

-

-

-

-

FeHyd

4 entries

H2:NAD+ oxidoreductase

-

-

-

-

H2ase

2 entries

Hox

5 entries

Hox hydrogenase

3 entries

Hox type hydrogenase

2 entries

HoxE

3 entries

HoxEFUYH

3 entries

HoxF

4 entries

HoxFUYHI2

2 entries

HoxH

5 entries

HoxS

2 entries

HoxU

3 entries

HoxY

3 entries

hydrogen-evolving enzyme

Frankia sp. R43

P22317

-

655638

hydrogenase

-

-

-

-

Hyn

4 entries

iron-hydrogenase

2 entries

NAD+-reducing hydrogenase

Cupriavidus necator

-

-

439633

NAD+-reducing NiFe hydrogenase

Thiocapsa roseopersicina

Q6XQK5

-

654285

NAD+-reducing [NiFe]-hydrogenase

2 entries

NAD-dependent hydrogenase

2 entries

NAD-reducing hydrogenase

Cupriavidus necator

-

-

654562, 674165

NADH-dependent Fe-only hydrogenase

Caldanaerobacter subterraneus subsp. tengcongensis

-

-

656734

NiFe hydrogenase

Thiocapsa roseopersicina

Q6XQK5

-

654285

NiFe-type reversible hydrogenase

Synechocystis sp. PCC 6803

-

-

704766

SH

3 entries

soluble hydrogenase

Cupriavidus necator

-

-

439633, 654562

soluble [NiFe]-hydrogenase

2 entries

[FeFe] hydrogenase

2 entries

[FeFe]-hydrogenase

4 entries

[NiFe] H2ase

Escherichia coli

-

-

687407

[NiFe] hydrogenase

5 entries

[NiFe]-hydrogenase

8 entries

FeHyd

Methanospirillum hungatei

-

-

712972

FeHyd

Methanospirillum hungatei JF-1 (DSM 864)

-

-

-

FeHyd

Syntrophobacter fumaroxidans

-

-

712972

FeHyd

Syntrophobacter fumaroxidans MPOB (DSM 10017)

-

-

-

H2ase

Thermotoga maritima

-

-

712281

H2ase

Thermotoga maritima DSM 3109

-

-

-

Hox

Cupriavidus necator

P22319

-

742575

Hox

Cupriavidus necator ATCC 17699

P22319

-

-

Hox

Synechocystis sp.

-

-

704606

Hox

Synechocystis sp. PCC 6803

-

-

704766, 742858

Hox

Thiocapsa roseopersicina

Q6XQK5

-

654285

Hox hydrogenase

Synechocystis sp. PCC 6803

-

-

743797

Hox hydrogenase

Thiocapsa roseopersicina

-

-

685324

Hox hydrogenase

Thiocapsa roseopersicina Bbs

-

-

-

Hox type hydrogenase

Gloeocapsa alpicola

-

-

672282

Hox type hydrogenase

Gloeocapsa alpicola CALU 743

-

-

-

HoxE

Synechocystis sp.

Q9Z354

-

654821

HoxE

Synechocystis sp. PCC 6803

-

-

704766

HoxE

Synechocystis sp. PCC 6803

-

subunit

742373

HoxEFUYH

Synechocystis sp.

-

-

687403

HoxEFUYH

Thiocapsa roseopersicina

-

-

685324

HoxEFUYH

Thiocapsa roseopersicina Bbs

-

-

-

HoxF

Cupriavidus necator

P22317

-

726282

HoxF

Cupriavidus necator DSM 428

P22317

-

-

HoxF

Synechocystis sp. PCC 6803

-

-

704766

HoxF

Synechocystis sp. PCC 6803

-

subunit

742373

HoxFUYHI2

Cupriavidus necator

-

hexameric enzyme form

674924

HoxFUYHI2

Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1

-

hexameric enzyme form

-

HoxH

Cupriavidus necator

P22319, P22320

-

724910

HoxH

Cupriavidus necator DSM 428

P22319, P22320

-

-

HoxH

Synechocystis sp.

-

subunit

742695

HoxH

Synechocystis sp. PCC 6803

-

-

704766

HoxH

Synechocystis sp. PCC 6803

-

subunit

742373

HoxS

Cupriavidus necator

P22319, P22320

-

724910

HoxS

Cupriavidus necator DSM 428

P22319, P22320

-

-

HoxU

Cupriavidus necator

P22318

-

726282

HoxU

Cupriavidus necator DSM 428

P22318

-

-

HoxU

Synechocystis sp. PCC 6803

-

-

704766

HoxY

Synechocystis sp.

-

subunit

742695

HoxY

Synechocystis sp. PCC 6803

-

-

704766

HoxY

Synechocystis sp. PCC 6803

-

subunit

742373

Hyn

Methanospirillum hungatei

-

-

712972

Hyn

Methanospirillum hungatei JF-1 (DSM 864)

-

-

-

Hyn

Syntrophobacter fumaroxidans

-

-

712972

Hyn

Syntrophobacter fumaroxidans MPOB (DSM 10017)

-

-

-

iron-hydrogenase

Thermotoga maritima

-

-

712281

iron-hydrogenase

Thermotoga maritima DSM 3109

-

-

-

NAD+-reducing [NiFe]-hydrogenase

Cupriavidus necator

-

-

656298, 674924

NAD+-reducing [NiFe]-hydrogenase

Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1

-

-

-

NAD-dependent hydrogenase

Cupriavidus necator

-

-

654782

NAD-dependent hydrogenase

Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1

-

-

-

SH

Cupriavidus necator

-

-

439633, 654562, 655890, 656298

SH

Cupriavidus necator

-

i.e. soluble cytoplasmic hydrogenase

656298

SH

Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1

-

-

-

soluble [NiFe]-hydrogenase

Cupriavidus necator

-

-

655890, 656298

soluble [NiFe]-hydrogenase

Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1

-

-

-

[FeFe] hydrogenase

Thermotoga maritima

-

-

712281

[FeFe] hydrogenase

Thermotoga maritima DSM 3109

-

-

-

[FeFe]-hydrogenase

Methanospirillum hungatei

-

-

712972

[FeFe]-hydrogenase

Methanospirillum hungatei JF-1 (DSM 864)

-

-

-

[FeFe]-hydrogenase

Syntrophobacter fumaroxidans

-

-

712972

[FeFe]-hydrogenase

Syntrophobacter fumaroxidans MPOB (DSM 10017)

-

-

-

[NiFe] hydrogenase

Allochromatium vinosum

-

-

684199

[NiFe] hydrogenase

Cupriavidus necator

-

-

439633

[NiFe] hydrogenase

Synechocystis sp.

-

-

742695

[NiFe] hydrogenase

synthetic construct

-

-

706499

[NiFe] hydrogenase

Thermococcus kodakarensis

-

-

684181, 688938

[NiFe]-hydrogenase

Cupriavidus necator

-

-

655890

[NiFe]-hydrogenase

Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1

-

-

-

[NiFe]-hydrogenase

Escherichia coli

-

-

687407

[NiFe]-hydrogenase

Methanospirillum hungatei

-

-

712972

[NiFe]-hydrogenase

Methanospirillum hungatei JF-1 (DSM 864)

-

-

-

[NiFe]-hydrogenase

Solidesulfovibrio fructosivorans

-

-

689959

[NiFe]-hydrogenase

Syntrophobacter fumaroxidans

-

-

712972

[NiFe]-hydrogenase

Syntrophobacter fumaroxidans MPOB (DSM 10017)

-

-

-