1.12.1.2: hydrogen dehydrogenase
This is an abbreviated version!
For detailed information about hydrogen dehydrogenase, go to the full flat file.
Word Map on EC 1.12.1.2
-
1.12.1.2
-
alcaligenes
-
eutrophus
-
hydrogenases
-
ralstonia
-
hydrogen-oxidizing
-
h2-dependent
-
lithoautotrophic
-
thiocapsa
-
roseopersicina
-
h2-oxidizing
-
oxygen-tolerant
-
synthesis
- 1.12.1.2
- alcaligenes
- eutrophus
- hydrogenases
-
ralstonia
-
hydrogen-oxidizing
-
h2-dependent
-
lithoautotrophic
-
thiocapsa
- roseopersicina
-
h2-oxidizing
-
oxygen-tolerant
- synthesis
Reaction
Synonyms
bidirectional hydrogenase, bidirectional Ni-Fe hydrogenase, bidirectional NiFe-hydrogenase, bidirectional [NiFe] hydrogenase, dehydrogenase, hydrogen, FeHyd, H2:NAD+ oxidoreductase, H2ase, Hox, Hox hydrogenase, Hox type hydrogenase, HoxE, HoxEFUYH, HoxF, HoxFUYHI2, HoxH, HoxS, HoxU, HoxY, hydrogen-evolving enzyme, hydrogenase, Hyn, iron-hydrogenase, NAD+-reducing hydrogenase, NAD+-reducing NiFe hydrogenase, NAD+-reducing [NiFe]-hydrogenase, NAD-dependent hydrogenase, NAD-reducing hydrogenase, NADH-dependent Fe-only hydrogenase, NiFe hydrogenase, NiFe-type reversible hydrogenase, SH, soluble hydrogenase, soluble [NiFe]-hydrogenase, [FeFe] hydrogenase, [FeFe]-hydrogenase, [NiFe] H2ase, [NiFe] hydrogenase, [NiFe]-hydrogenase
ECTree
1.12.1.2 hydrogen dehydrogenaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 1.12.1.2 - hydrogen dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
H2 + oxidized methyl viologen
H+ + reduced methyl viologen
the artificial electron donor is accepted by the cells for H2 production when added to the culture medium
-
-
r
H2 + NAD+
H+ + NADH
-
utilization of H2 as energy source during autotrophic growth on hydrogen and CO2
-
r
H2 + NAD+
H+ + NADH
-
utilization of H2 as energy source during autotrophic growth on hydrogen and CO2
-
r
H2 + NAD+
H+ + NADH
-
enzyme provides reducing equivalents for CO2 fixation
-
-
r
H2 + NAD+
H+ + NADH
-
the enzyme catalyzes electron transfer from molecular hydrogen to NAD+, thereby producing reducing equivalents for CO2 fixation in the form of NADH
-
-
?
H2 + NAD+
H+ + NADH
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
-
utilization of H2 as energy source during autotrophic growth on hydrogen and CO2
-
r
H2 + NAD+
H+ + NADH
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
-
key enzyme in H2 metabolism
-
-
r
H2 + NAD+
H+ + NADH
-
physiological function of the enzyme in Frankia strains, overview
-
-
r
H2 + NAD+
H+ + NADH
H2 producing activity is not dependent on NAD+ reduction
-
-
r
H2 + NAD+
H+ + NADH
-
enzyme delivers hydrogen-driven reducing power for methane oxidation
-
-
r
H2 + NAD+
H+ + NADH
in vivo H2 evolution under nitrogenase-repressed conditions
-
-
r
additional information
?
-
-
at high H2 partial pressure enzyme activity is reduced and fermentation is partially shifted to ethanol production
-
-
?
additional information
?
-
-
activity is equally high in atmosperes of 20% O2, 20% N2, or 100% H2, the latter being slightly preferred
-
-
?
additional information
?
-
-
enzyme regulation involves a regulatory hydrogenase RH which acts as a sensor for H2 content, interaction via signal cascade
-
-
?
additional information
?
-
-
the organism can grow on H2 as sole energy source in an oxic environment
-
-
?
additional information
?
-
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
-
the organism can grow on H2 as sole energy source in an oxic environment
-
-
?
additional information
?
-
enzyme is the key enzyme in hydrogen metabolism, no activity in strain R43 under aerobic nitrogen-limited conditions
-
-
?
additional information
?
-
enzyme is the key enzyme in hydrogen metabolism, no activity in strain R43 under aerobic nitrogen-limited conditions
-
-
?
additional information
?
-
enzyme is the key enzyme in hydrogen metabolism, no activity in strain R43 under aerobic nitrogen-limited conditions
-
-
?
additional information
?
-
enzyme is the key enzyme in hydrogen metabolism, no activity in strain R43 under aerobic nitrogen-limited conditions
-
-
?
additional information
?
-
-
physiological role of the hydrogenase seems to be equally associated with both formation and uptake of H2, depending on the redox state of the intracellular medium
-
-
?
additional information
?
-
-
physiological role of the hydrogenase seems to be equally associated with both formation and uptake of H2, depending on the redox state of the intracellular medium
-
-
?
