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1.11.2.2: myeloperoxidase

This is an abbreviated version!
For detailed information about myeloperoxidase, go to the full flat file.

Word Map on EC 1.11.2.2

Reaction

Cl-
+
H2O2
 +
H+
=
HClO
 +
H2O

Synonyms

donor, hydrogen peroxide oxidoreductase, donor, hydrogen peroxideoxidoreductase, donor: H2O2 oxidoreductase, donor:H2O2 oxidoreductase, donor:hydrogen peroxide oxidoreductase, donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7, epx2a, hemi-MPO, hemi-myeloperoxidase, LPO, MPO, MPX, myeloperoxidase, peroxinectin, properoxinectin, recombinant human MPO, rhMPO, tissue myeloperoxidase

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.2 Peroxygenases
                1.11.2.2 myeloperoxidase

pH Optimum

pH Optimum on EC 1.11.2.2 - myeloperoxidase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.5 - 5
4.7 - 6
-
optimum pH for peroxidase activity of MPO
5.8
-
with 0.002 mM ascorbic acid as activator
7.4
-
optimum pH for chlorinating activity of MPO, at pH 7.4 chloride ions do not compete with guaiacol up to the concentration of 150 mM