1.11.1.8: iodide peroxidase

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For detailed information about iodide peroxidase, go to the full flat file.

Word Map on EC 1.11.1.8

1.11.1.8

thyroglobulin

tsh

autoimmune

hypothyroidism

autoantibody

thyroxin

women

graves

tpoabs

hashimoto

thyrotropin

thyroid-stimulating

pregnancy

subclinical

euthyroidism

triiodothyronine

goiter

follicular

overt

thyrocytes

anti-tpo

antithyroid

symporter

organification

trimester

levothyroxine

autoantigens

thyroid-specific

frtl-5

guaiacol

methimazole

lactoperoxidase

radioiodine

propylthiouracil

goitrous

thyrotoxicosis

antibody-negative

multinodular

analysis

peroxidase-catalyzed

hypothalamic-pituitary-thyroid

ophthalmopathy

gadas

tsh-induced

anti-thyroglobulin

medicine

thyroid-associated

tsh-stimulated

chloroperoxidase

synthesis

nodosum

haloperoxidases

thyrotoxic

Reaction

2 iodide +

+ 2 H+ =

+ 2 H2O

Synonyms

bromoperoxidase, high-molecular weight-thyroid peroxidase, HMW-TPO, hrTPO, hTPO, iodide peroxidase-tyrosine iodinase, iodinase, iodoperoxidase (heme type), thyroid peroxidase, thyroperoxidase, TPO, TPOX, TPQ, tyrosine iodinase, vanadium bromoperoxidase, vBPO

ECTree

1 Oxidoreductases

1.11 Acting on a peroxide as acceptor

1.11.1 Peroxidases

1.11.1.8 iodide peroxidase

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Results	in table
7	Activating Compound
409	AA Sequence
11	Application
1	CAS Registry Number
14	Cloned(Commentary)
11	Cofactor
3635	Disease/ Diagnostics
1	Expression
3	General Information
1	General Stability
6	IC50 Value
90	Inhibitors
8	Ki Value [mM]
14	KM Value [mM]
28	Localization
21	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
65	Organism
5	Pathway
2	PDB ID
3	pH Optimum
2	pH Range
3	pI Value
10	Posttranslational Modification
15	Protein Variants
14	Purification (Commentary)
5	Reaction
5	Reaction Type
65	Reference
59	Source Tissue
12	Specific Activity [micromol/min/mg]
7	Storage Stability
65	Substrates and Products (Substrate)
9	Subunits
47	Synonyms
1	Systematic Name
1	Temperature Stability [°C]
7	Turnover Number [1/s]

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34.6

3,3',5,5'-tetramethylbenzidine

Homo sapiens

pH 5.5

658139

11.9

3,3'-dimethoxybenzidine

Homo sapiens

pH 5.5

658139

27.5

3,3'-dimethylbenzidine

pH 5.5

benzidine

pH 5.5

Br-

I-

in phosphate buffer (100 mM, pH 8.0), at 20°C

684414