Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.11.1.20: prostamide/prostaglandin F2alpha synthase

This is an abbreviated version!
For detailed information about prostamide/prostaglandin F2alpha synthase, go to the full flat file.

Reaction

thioredoxin
+
(5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate
=
thioredoxin disulfide
+
(5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dienoate

Synonyms

PGF prostamide F synthase, PM/PGFS, Pmpgfs, prostaglandin F ethanolamide synthase, prostamide F synthase, prostamide/PGF synthase, prostamide/prostaglandin F synthase

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.20 prostamide/prostaglandin F2alpha synthase

Reference

Reference on EC 1.11.1.20 - prostamide/prostaglandin F2alpha synthase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moriuchi, H.; Koda, N.; Okuda-Ashitaka, E.; Daiyasu, H.; Ogasawara, K.; Toh, H.; Ito, S.; Woodward, D.F.; Watanabe, K.
Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily
J. Biol. Chem.
283
792-801
2008
Sus scrofa (A9CQL8), Sus scrofa, Mus musculus (Q9DB60), Mus musculus
Manually annotated by BRENDA team
Yoshikawa, K.; Takei, S.; Hasegawa-Ishii, S.; Chiba, Y.; Furukawa, A.; Kawamura, N.; Hosokawa, M.; Woodward, D.F.; Watanabe, K.; Shimada, A.
Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system
Brain Res.
1367
22-32
2011
Mus musculus
Manually annotated by BRENDA team
Urquhart, P.; Nicolaou, A.; Woodward, D.
Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases
Biochim. Biophys. Acta
1851
366-376
2015
Rattus norvegicus
Manually annotated by BRENDA team
Silvestri, C.; Martella, A.; Poloso, N.J.; Piscitelli, F.; Capasso, R.; Izzo, A.; Woodward, D.F.; Di Marzo, V.
Anandamide-derived prostamide F2alpha negatively regulates adipogenesis
J. Biol. Chem.
288
23307-23321
2013
Mus musculus
Manually annotated by BRENDA team
Woodward, D.F.; Wang, J.W.; Poloso, N.J.
Recent progress in prostaglandin F2alpha ethanolamide (prostamide F2alpha) research and therapeutics
Pharmacol. Rev.
65
1135-1147
2013
Mus musculus
Manually annotated by BRENDA team
Iwasa, K.; Yamamoto, S.; Takahashi, M.; Suzuki, S.; Yagishita, S.; Awaji, T.; Maruyama, K.; Yoshikawa, K.
Prostaglandin F2alpha FP receptor inhibitor reduces demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
Prostaglandins Leukot. Essent. Fatty Acids
91
175-182
2014
Mus musculus
Manually annotated by BRENDA team
Bertrand, J.A.; Woodward, D.F.; Sherwood, J.M.; Spenlehauer, A.; Silvestri, C.; Piscitelli, F.; Marzo, V.D.; Yamazaki, M.; Sakimura, K.; Inoue, Y.; Watanabe, K.; Overby, D.R.
Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure
Prostaglandins Leukot. Essent. Fatty Acids
165
102235
2021
Mus musculus
Manually annotated by BRENDA team