1.10.3.15: grixazone synthase

This is an abbreviated version!
For detailed information about grixazone synthase, go to the full flat file.

Reaction

2 3-amino-4-hydroxybenzoate +

Synonyms

GriF

ECTree

     1 Oxidoreductases

         1.10 Acting on diphenols and related substances as donors

             1.10.3 With oxygen as acceptor

                1.10.3.15 grixazone synthase

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Results	in table
1	Activating Compound
4	AA Sequence
1	Cloned(Commentary)
2	General Information
15	Inhibitors
8	kcat/KM [mM/s]
7	Ki Value [mM]
6	KM Value [mM]
3	Metals/Ions
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
13	Organism
6	Pathway
2	pH Optimum
1	pH Range
1	pH Stability
1	Purification (Commentary)
1	Reaction
5	Reference
2	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.10.3.15 - grixazone synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2-amino-4-methylphenol + N-acetyl-L-cysteine + O2

?

Streptomyces griseus

-

-

674768

-

-

?

2-amino-4-methylphenol + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

3,4-dihydroxybenzaldehyde + N-acetyl-L-cysteine + O2

?

Streptomyces griseus

-

-

674768

-

-

?

3,4-dihydroxybenzaldehyde + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + O2

grixazone A + H2O + CO2

Streptomyces griseus

-

-

674768

-

-

?

3-amino-4-hydroxybenzaldehyde + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + O2

grixazone B + H2O + CO2

2 entries

4-amino-3-hydroxybenzoate + N-acetyl-L-cysteine + O2

?

Streptomyces griseus

-

-

674768

-

-

?

catechol + N-acetyl-L-cysteine + O2

?

Streptomyces griseus

-

-

674768

-

-

?

catechol + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

L-Dopa + N-acetyl-L-cysteine + O2

?

Streptomyces griseus

-

-

674768

-

-

?

L-DOPA + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

o-aminophenol + N-acetyl-L-cysteine + O2

2-aminophenoxazin-3-one + H2O + CO2

Streptomyces griseus

-

-

674768

-

-

?

o-aminophenol + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

protocatechuic acid + O2

?

Streptomyces griseus subsp. griseus

-

-

713565

-

-

?

additional information

?

-

Streptomyces griseus

-

the enzyme shows no monophenolase activity, although it oxidizes various o-aminophenols as preferable substrates rather than catechol-type substrates. The enzyme does not use tyrosine as a substrate

674768

-

-

?

3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + O2

grixazone B + H2O + CO2

Streptomyces griseus

-

-

674768, 722650

-

-

?

3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + O2

grixazone B + H2O + CO2

Streptomyces griseus IFO 13350

-

-

722650

-

-

?