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1.1.99.38: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)

This is an abbreviated version!
For detailed information about 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent), go to the full flat file.

Reaction

2-deoxy-scyllo-inosamine
+
S-adenosyl-L-methionine
=
3-amino-2,3-dideoxy-scyllo-inosose
+
5'-deoxyadenosine
+
L-methionine

Synonyms

BtrN, DOIA dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.38 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)

General Information

General Information on EC 1.1.99.38 - 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
gene disruption causes the interruption of the biosynthetic pathway between 2-deoxy-scyllo-inosamine and 2-deoxystreptamine. In vitro assay of the overexpressed enzyme reveals that the enzyme catalyzes the oxidation of 2-deoxy-scyllo-inosamine under strictly anaerobic conditions along with consumption of an equimolar amount of S-adenosyl-L-methionine to produce 5-deoxyadenosine, methionine, and 3-amino-2,3-dideoxy-scyllo-inosose