1.1.99.38: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
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For detailed information about 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent), go to the full flat file.
Reaction
Synonyms
BtrN, DOIA dehydrogenase
ECTree
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General Information
General Information on EC 1.1.99.38 - 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
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physiological function
gene disruption causes the interruption of the biosynthetic pathway between 2-deoxy-scyllo-inosamine and 2-deoxystreptamine. In vitro assay of the overexpressed enzyme reveals that the enzyme catalyzes the oxidation of 2-deoxy-scyllo-inosamine under strictly anaerobic conditions along with consumption of an equimolar amount of S-adenosyl-L-methionine to produce 5-deoxyadenosine, methionine, and 3-amino-2,3-dideoxy-scyllo-inosose