1.1.99.36: alcohol dehydrogenase (nicotinoprotein)
This is an abbreviated version!
For detailed information about alcohol dehydrogenase (nicotinoprotein), go to the full flat file.
Word Map on EC 1.1.99.36
-
1.1.99.36
-
nicotinoproteins
-
erythropolis
-
rhodococcus
-
dehydrogenases
-
methanolica
-
formaldehyde
-
amycolatopsis
-
nadp
-
n,n-dimethyl-4-nitrosoaniline
-
dismutase
-
methanol
-
synthesis
- 1.1.99.36
-
nicotinoproteins
- erythropolis
-
rhodococcus
- dehydrogenases
- methanolica
- formaldehyde
- amycolatopsis
- nadp
- n,n-dimethyl-4-nitrosoaniline
- dismutase
- methanol
- synthesis
Reaction
Synonyms
4-nitroso-N, N-dimethylaniline-dependent alcohol dehydrogenase, NDMA-ADH, NDMA-dependent alcohol dehydrogenase, np-ADH
ECTree
Advanced search results
Systematic Name
Systematic Name on EC 1.1.99.36 - alcohol dehydrogenase (nicotinoprotein)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ethanol:acceptor oxidoreductase
Contains Zn2+. Nicotinoprotein alcohol dehydrogenases are unique medium-chain dehydrogenases/reductases (MDR) alcohol dehydrogenases that have a tightly bound NAD+/NADH cofactor that does not dissociate during the catalytic process. Instead, the cofactor is regenerated by a second substrate or electron carrier. While the in vivo electron acceptor is not known, N,N-dimethyl-4-nitrosoaniline (NDMA), which is reduced to 4-(hydroxylamino)-N,N-dimethylaniline, can serve this function in vitro.
The enzyme from the Gram-positive bacterium Amycolatopsis methanolica can accept many primary alcohols as substrates, including benzylalcohol [1].